News

Mar 22, 2019

America's Health Insurance Plans and 16 other organizations questioned Congress to pass legislation setting reimbursement rates that would not increase premiums by basing amounts on market rates. This action was necessary as patients were left with thousands of dollars in unexpected medical bills. 

Mar 21, 2019

According to a report published in the Journal of the American Medical Informatics Association, if one receives consistent primary care it leads to better over all health. In spite of that telehealth does increase the risk of fragmentation if not handled appropriately. The researchers also added that 90 percent of telehealth users chose a video visit for convenience as it saved time. 

Mar 21, 2019

Scientists studying damaged brains of boxers and other sports people have found key details about a head injury-linked disease called “punch drunk syndrome” that could help the development of new diagnostics and treatments for Alzheimer’s.

Journal Abstracts

Mar 22, 2019

This study is to determine the genetic basis of central centrifugal cicatricial alopecia (CCCA). They used exome sequencing in a group of women with alopecia (discovery set), compared the results with those in a public repository, and applied other filtering criteria to identify candidate genes. Result suggest mutations in PADI3, which encodes a protein that is essential to a proper hair-shaft formation, were associated with CCCA. 

Mar 22, 2019

The aim of this study was to examine the prognostic value of the neutrophil-to-lymphocyte ratio (NLR) for patients with advanced gastric cancer receiving second-line chemotherapy. The association of overall survival (OS) in second-line chemotherapy and the clinicopathological findings including NLR were analyzed retrospectively.  Patients with advanced gastric cancer with performance status 2, hemoglobin < 10 g/dL, and NLR before first-line chemotherapy ≥3 are not likely to benefit from second-line chemotherapy.

Mar 22, 2019

This was an observational and retrospective and involved 30 patients to determine the rate of recurrence of this pathology in a series of arthroscopic patients & to assess patient satisfaction well after the operation. The 13% recurrence rate is on the average of what is observed. Later satisfaction with the intervention is very good, and complications remain rare.

 

Recent Articles

Mar 22, 2019

This was an observational and retrospective and involved 30 patients to determine the rate of recurrence of this pathology in a series of arthroscopic patients & to assess patient satisfaction well after the operation. The 13% recurrence rate is on the average of what is observed. Later satisfaction with the intervention is very good, and complications remain rare.

 

Mar 22, 2019

The aim of this study was to evaluate the prognostic factors, including the level of N1  lymph node (LN) involvement in non-small cell lung cancer (NSCLC). Patients were examined in terms of demographic characteristics, preoperative and postoperative management, survival rates, as well as variables affecting survival. Surgical-pN1 localization or pleural involvement does not have a significant effect on survival, whereas advanced age and further T classification affect survival adversely. Adjuvant therapy, on the other hand, has a significantly positive effect on survival.

Mar 22, 2019

An 8-month-old female with EBV infection developed obstructive jaundice 2 weeks after the initial infection. Radiology investigations showed choledochal cyst type IVa complicated by stone formation in the common bile duct. She was managed with complete resection of extrahepatic ducts with Roux-en-Y hepaticoenterostomy. 

Clinical Research

Mar 21, 2019

This phase I, interventional trial studies the side effects and best dose of paclitaxel albumin-stabilized nanoparticle formulation and bevacizumab in treating patients with stage IV melanoma that cannot be removed by surgery. Drugs used in chemotherapy, such as paclitaxel albumin-stabilized nanoparticle formulation, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways.

Mar 21, 2019

This is a prospective, single center, double-blind, randomized, two-arm feasibility study to see if it is safe to give patients with pancreatic or head and neck cancer a low dose of the FDA approved anesthetic drug ketamine at the same time they receive radiation and/or chemotherapy for their cancer treatment to prevent depression and its effects. Approximately 40 patients with head and neck cancer or pancreatic cancer about to undergo cancer therapy will be randomized 1:1 to receive study treatment with weekly oral administration of 0.5 mg/kg ketamine (Arm A) or weekly oral administration of placebo (Arm B).

Mar 21, 2019

The proposed phase I, the non-randomized, interventional clinical trial will investigate the safety and tolerability of 177Lu-CYT-500 in patients with metastatic prostate cancer and determine the optimal antibody mass and a dose of 177Lu to be used for further study. Patients with histologically documented prostate cancer that is progressing following castration will be eligible.

Mar 21, 2019

This is a pilot trial to observe the post-operative effects of statin for thromboprophylaxis & cardiovascular outcomes protection. In this pilot study, the investigators will treat 30 orthopedic surgery patients (hip fracture, hip or knee arthroplasty) with either atorvastatin or placebo (a capsule with no study drug).  The investigators hypothesize that atorvastatin will lessen the degree of postoperative inflammation found in these patients. 

Mar 21, 2019

This is an interventional, randomized trial where they study a technology-assisted care transition intervention for veterans with CHF or COPD (TACT). The investigators will implement and evaluate a virtual nurse intervention to provide automated, tailored, and timely support to Veterans transitioning from hospital to home. As effective care transition interventions incorporate both inpatient and outpatient components, the virtual nurse will first engage with patient onscreen during their inpatient stay and then via text message post-discharge.

Mar 19, 2019

 

Degenerative dementias including Alzheimer's Disease (AD), Parkinson's Disease with Dementia (PDD), Dementia with Lewy Bodies (DLB), Frontotemporal Dementias (FTLD), Corticobasal Degeneration (CBD) and Progressive Supranuclear Palsy (PSP) constitute a significant, and growing burden with an estimated cost to the US healthcare system for 2016 of $236 Billion. Definitive diagnosis of these dementias is based on pathological criterion upon autopsy, which presents a significant challenge to establish diagnosis in living patients. Although clinical diagnostic criteria have been developed for several of these disorders, including for Alzheimer's Disease (AD) by the National Institute of Neurological and Communicative Disorders and Stroke and Alzheimers Disease and Related Disorders Association (NINCDS-ADRDA) , Parkinson's Disease (PD) by the United Kingdom Parkinson Disease Brain Bank Diagnostic Criteria (UKPDBB) diagnostic criteria for Parkinson Disease(4) and others, the currently available tests, including the use of imaging markers and Cerebrospinal Fluid (CSF) biological markers do not provide a definite diagnosis since this requires the observation of characteristic neuropathological changes in specific regions of the brain.

Mar 19, 2019

This study is intended to observe the therapeutic effect of dydrogesterone on endometrial polyps and provide a reference for clinical treatment.

Publications

Mar 20, 2019

Pediatric Pulmonology is a global journal studying the respiratory system in disease and in health as it develops from intrauterine life though adolescence to adulthood. The current issue consists of case reports on Cystic Fibrosis and Pulmonary Dysplasia and much more. 

Mar 20, 2019

Journal of Hypertension Research is a monthly journal focusing on current updates in the treatment of Hypertension. It also consists of case-reports, case-studies covering hot topics related to Hypertension. The current issue consists of articles on Hypertensive Heart Failure, Subclinical vascular damage in Hypertension etc. 

Mar 20, 2019

The Journal of Diabetes Investigation is a monthly journal focusing on embracing clinical and experimental research in diabetes and related areas. The journal also includes aspects of prevention, treatment, as well as molecular aspects and pathophysiology. The current issue consists of various articles including Gestational Diabetes etc. 

Mar 20, 2019

Clinical Colorectal Cancer is a peer-reviewed, quarterly journal that publishes original articles describing various aspects of clinical and translational research of gastrointestinal cancers. The articles are published are inclusive of clinical research and mechanistic approaches; drug sensitivity and resistance; gene and antisense therapy; pathology, markers, and prognostic indicators; chemoprevention strategies; multimodality therapy; and integration of various approaches. 

Mar 20, 2019

Medical Image Analysis publishes the highest quality, original papers that contribute to the basic science of processing, analysing and utilizing medical and biological images. The articles primarily focus on utilizing biomedical image datasets at all spatial scales, ranging from molecular/cellular imaging to tissue/organ imaging. 

Mar 20, 2019

Bladder Cancer publishes research reports, reviews, short communications, and letters-to-the-editor. The journal is dedicated to providing an open forum for original research in basic science, translational research and clinical medicine that expedites our fundamental understanding and improves treatment of tumors of the bladder and upper urinary tract.

Mar 20, 2019

An International Multidisciplinary Journal of the Schizophrenia International Research Society, Schizophrenia Research is the journal of choice for international researchers and clinicians to share their work with the global schizophrenia research community. More than 6000 institutes have online or print (or both) access to this journal.

Videos

Mar 22, 2019

Watch UCLA neurosurgeon- Dr. Won Kim, MD, and head & neck surgeon- Dr. Jivianne Lee, MD, give an overview of endoscopic surgery to remove sinonasal tumors that originate from within the nasal cavities and sinuses. These techniques allow a multidisciplinary team of surgeons, including ENT, neurosurgery and ophthalmology specialists, to tackle these challenging tumors through the nose, without any external incisions.

Mar 22, 2019

Watch UCLA neurosurgeon- Dr. Won Kim, MD, and head & neck surgeon- Dr. Jivianne Lee, MD, give an overview of endoscopic surgery to remove sinonasal tumors that originate from within the nasal cavities and sinuses. These techniques allow a multidisciplinary team of surgeons, including ENT, neurosurgery and ophthalmology specialists, to tackle these challenging tumors through the nose, without any external incisions.

Mar 22, 2019

Watch as Drs. Jerry Rozeboom and Owen McCarron from OB-GYN Associates give you step-by-step descriptions during the robotic hysterectomy procedure.

Mar 22, 2019

A large basilar trunk aneurysm was incidentally found in a 77-year-old woman in the examination for headache. Though it was asymptomatic, high signal intensity was noticed in the brainstem around the aneurysm on FLAIR image of MRI. As she was otherwise healthy, surgical clipping was performed through an anterior temporal approach.

 

Case Studies

Mar 22, 2019

An 8-month-old female with EBV infection developed obstructive jaundice 2 weeks after the initial infection. Radiology investigations showed choledochal cyst type IVa complicated by stone formation in the common bile duct. She was managed with complete resection of extrahepatic ducts with Roux-en-Y hepaticoenterostomy. 

Mar 22, 2019

A 55-year-old male with hypertension presented with dyspnea on exertion and chest pain. TTE showed mitral valve prolapse with moderate to severe mitral regurgitation and an atrial fibrous band. The patient had poor exercise tolerance and thus he was surgically treated with a mitral annuloplasty.

Mar 22, 2019

A 32-year-old nulliparous female came for evaluation and treatment of a newly diagnosed Malignant struma ovarii. Based on her clinical history, indeterminate cytopathology, and patient preference, the decision was made to perform total thyroidectomy. Her recovery was complicated with hypocalcemia and follow-up post three months did not show any evidence of metastatic disease. 

Mar 22, 2019

A 58-year-old female patient presented with angiolipofibroma of sigmoid colon that was discovered as a rounded mass protruded from anus during defecation and reduced manually by herself. She had no history of abdominal pain, bleeding per rectum. She was treated successfully with surgical resection.