News

Nov 15, 2019

In the study, researchers examined differentially affected regions in the lungs obtained from individuals with idiopathic pulmonary fibrosis (IPF) and found that what looks like normal lung is already undergoing changes in specific genes. They then tracked how these genes continue to change, increasing or decreasing, as the disease progresses.

Nov 15, 2019

In the study, researchers examined differentially affected regions in the lungs obtained from individuals with idiopathic pulmonary fibrosis (IPF) and found that what looks like normal lung is already undergoing changes in specific genes. They then tracked how these genes continue to change, increasing or decreasing, as the disease progresses.

Nov 15, 2019

A recent report suggests that plans for the merger Midwestern health systems UnityPoint Health and Sanford Health have been called off. This whole merger was supposed to be worth $11 billion however the merger was called off saying that the two organizations were both "high-performing systems" with "unique strengths and cultures," and said they would work together in the future to benefit the systems. 

Journal Abstracts

Nov 19, 2019

JingLi et.al. conducted a study to evaluate the effects of hepatic and renal impairment on pharmacokinetics and tolerability following a single 84-mg dose of eliglustat. The researchers concluded that Higher exposures of eliglustat at steady-state were predicted using a physiologically-based pharmacokinetic model after repeated 84-mg eliglustat doses.

Nov 19, 2019

Pin Wang et.al. conducted a study to assess the tumour incidence and spectrum in order to identify novel disease models and genes that contribute to human disease. The researchers concluded that Collaborative Cross strains tremendous variation in tumour susceptibility. 

Nov 19, 2019

Felicitas U. Idigo et.al. conducted a study conducted a study to determine if lipid profile parameters could serve as predictors of carotid intima-media thickness. The researchers concluded that they are not significant predictors and thus combining them with CIMT does not improve the diagnostic sensitivity of sonography in atherosclerosis screening.

Recent Articles

Nov 19, 2019

Pin Wang et.al. conducted a study to assess the tumour incidence and spectrum in order to identify novel disease models and genes that contribute to human disease. The researchers concluded that Collaborative Cross strains tremendous variation in tumour susceptibility. 

Nov 19, 2019

Pin Wang et.al. conducted a study to assess the tumour incidence and spectrum in order to identify novel disease models and genes that contribute to human disease. The researchers concluded that Collaborative Cross strains tremendous variation in tumour susceptibility. 

Nov 19, 2019

Felicitas U. Idigo et.al. conducted a study conducted a study to determine if lipid profile parameters could serve as predictors of carotid intima-media thickness. The researchers concluded that they are not significant predictors and thus combining them with CIMT does not improve the diagnostic sensitivity of sonography in atherosclerosis screening.

Clinical Research

Nov 18, 2019

Stanford University is conducting an Interventional Trial in 360 participants in order to to expand the differential diagnosis and provide an evidence--based therapy for the large population of patients with angina in the absence of obstructive CAD who currently remain undiagnosed and untreated.

Nov 18, 2019

Thyroid nodules are a common presentation in the clinic, with an increasing incidence, especially in women. Assiut University is conducting an Observational Study in order to determine a Clinical Diagnostic Approach in the cases of a Thyroid Nodule. 

Nov 18, 2019

McMaster University is conducting a study is to investigate if low level laser therapy will do more good than harm for patients with severe refractory fecal incontinence. It is a proof of concept study without a placebo arm.The therapy consists of a 3 week treatment with a total of 8 sessions of low level laser therapy. Effects will be assessed using symptoms and quality of life questionnaires and physiological assessments of pelvic floor function, at 4 weeks and 12 weeks after beginning of treatment.

Nov 18, 2019

McMaster University is conducting a study is to investigate if low level laser therapy will do more good than harm for patients with severe refractory fecal incontinence. It is a proof of concept study without a placebo arm.The therapy consists of a 3 week treatment with a total of 8 sessions of low level laser therapy. Effects will be assessed using symptoms and quality of life questionnaires and physiological assessments of pelvic floor function, at 4 weeks and 12 weeks after beginning of treatment.

Nov 18, 2019

Pectus excavatum is the most common anterior chest wall deformity that affects up to 1:400 of newborns. Zuyderland Medisch Centrum is conducting an Interventional trial in 25 participants in order to understand the Quantification of Chest Wall Changes in cases after Nuss Bar Removal using the Three-dimensional Optical Surface Scans. 

Nov 18, 2019

The objective of the study is to evaluate the safety and efficacy of the home-use device Silk'n toothbrush (ToothWave) for the improvement in dental health through the reduction of plaque, gingivitis, and calculus.

Nov 18, 2019

The Apollo Study being conducted by the Carolina Institute for Clinical Research, which is enrolling now, is researching a new investigational drug for OAB.

Publications

Nov 18, 2019

This book addresses all aspects of orthopedic microsurgery, from the development of the principles to their applications. Replantation of fingers, hands and extremity parts are well summarized by highly experienced microsurgical surgeons. The methods for tissue transplantation and microsurgical reconstruction of tissue defects, which have been proved to be successful tools for saving severely injured extremities, were developed by experienced orthopedic surgeons in cooperation with plastic surgeons. 

Nov 18, 2019

This book provides a comprehensive overview of the "real-time accompany technique" for diagnostic interventional pulmonology, known as rapid on-site evaluation (ROSE). It also offers readers a detailed understanding of how to interpret ROSE cytological slides, which is key to the interventional procedure itself and valuable in the analysis of the infectious disease status.

Nov 18, 2019

Advances in Integrative Dermatology offers a comprehensive survey of this dynamic field, providing up-to-date information on both preventative and therapeutic approaches to skin health. Combining clinical medicine with complementary treatment plans, integrative dermatology provides an innovative perspective to individual patient care. This essential text explores new research in areas including the effects of stress and pollution on the skin, the importance of high-quality sleep, complementary methods of averting skin conditions, and more.

Nov 18, 2019

This new edition provides an update on the current state of the art of cancer chemotherapy and clinical practice and presents new pipeline anticancer agents and promising therapeutic strategies that are emerging alongside new breakthroughs in cancer biology. Its unique approach enables students to gain an understanding of the pathological, physiological, and molecular processes governing malignancy, while also introducing the role of health professionals and scientists in the research and treatment of cancer.

Nov 18, 2019

Tinnitus: A Multidisciplinary Approach provides a broad account of tinnitus and hyperacusis, detailing the latest research and developments in clinical management, incorporating insights from audiology, otology, psychology, psychiatry, and auditory neuroscience. It promotes a collaborative approach to treatment that will benefit patients and clinicians alike. The 2nd edition has been thoroughly updated and revised in line with the very latest developments in the field. 

Nov 15, 2019

This text provides a comprehensive and contemporary discussion of current indications, techniques, technology, and results in ureteroscopy from the world leaders who perform this procedure.  It provides not only the latest literature and data regarding URS but also tips and tricks for the reader when performing various URS procedures.  

Nov 15, 2019

This book includes research that combines biological, psychological and socio-cultural perspectives and covers areas that are relevant to clinicians, public health practitioners, researchers, policy makers and students from diverse disciplines in high-, low- and middle-income countries.

Videos

Nov 15, 2019

Join UCLA oncologist Monica Mead, MD, for an overview of treatment options for patients diagnosed with diffuse large B-cell lymphoma (DLBCL) and other follicular lymphomas.

Nov 15, 2019

Join UCLA oncologist Monica Mead, MD, for an overview of treatment options for patients diagnosed with diffuse large B-cell lymphoma (DLBCL) and other follicular lymphomas.

Nov 15, 2019

Watch Dr. Iype Cherian performing Scientific presentation on Telovelar Approach to Brainstem Glioma.

Nov 15, 2019

Richard E. Link, MD, Ph.D., provides an overview of the critical anatomic features of horseshoe kidneys in adults and how these features should factor into treatment decision-making. He describes how the presence of a horseshoe kidney can affect the management of ureteral obstruction and nephrolithiasis, and technical surgical considerations in these cases.

Case Studies

Nov 18, 2019

Stiff-person syndrome (SPS) is an uncommon neurological disorder characterized by significant rigidity and muscle spasms primarily affecting the truncal and proximal musculature. Furthermore, a wide-based gait with functional impairment is generally seen. High-dose benzodiazepines or baclofen are widely considered the optimal initial therapy; however, major adverse effects often preclude adequate dosing. Refractory cases may be treated with intravenous immunoglobulins (IVIG), plasma exchange, or B-cell depletion with rituximab, although these are also associated with major, sometimes fatal, adverse reactions. Several reports have validated the safety and utility of botulinum injections in this setting, yet botulinum remains markedly underutilized in this cohort. This case report shows that botulinum can decrease pain and stiffness, improve gait and balance, and decrease dependence on powerful systemic treatments in this group.

Nov 18, 2019

Pimpiroon Ploysangam and Sangita P. Patel report a 51-year-old patient with visually significant confluent central guttae from FECD who underwent a successful DSO with immediate post-operative use of the Rho-associated protein kinase (ROCK) inhibitor (netarsudil). They report the preoperative and post-operative slit lamp images, specular microscopy data, and corneal topography, thickness, and densitometry data. These represent a unique data set for this new surgical treatment option for FECD. Despite a small descemetorhexis, they show the improvement in corneal thickness and opacity extends beyond the boundaries of the descemetorhexis. Early initiation of a ROCK inhibitor was a successful treatment for this patient.

Nov 18, 2019

Jessian L. Munoz et al present a case of maternal-fetal hemorrhage characterized by intermittently reassuring fetal testing. Additional testing performed with ultrasound, including middle cerebral artery (MCA) doppler waveforms, confirmed fetal hemorrhage followed by emergent cesarean section. This report highlights the acute usage of MCA dopplers in obstetric decision making. The Newborn required transfusion but otherwise recovered well. MCA may be a useful tool for fetal assessment in Labor and Delivery units.

Nov 18, 2019

A 76-year-old Japanese man presented with a primary complaint of reduced visual acuity in his right eye. On initial examination, the visual acuity in his right and left eye was 0.4 and 0.01, respectively. He had previously been diagnosed as having macular degeneration of unknown origin in his left eye. Optical coherence tomography imaging confirmed vitreomacular traction and impending macular hole in his right eye. After a 1-week follow-up period, posterior vitreous detachment was detected, and the impending macular hole appeared to be resolved. Two months later, the impending macular hole had completely disappeared and his visual acuity had improved to 0.9. Six months later, he again noticed decreased vision in his right eye. An examination revealed that his visual acuity had dropped to 0.4, and there was a recurrence of impending macular hole. An optical coherence tomography examination showed no definitive findings of vitreous traction, and, 1 month later, spontaneous disappearance was observed again and his visual acuity improved to 0.7.