News

Feb 20, 2020

According to a recent study, Zoster Vaccine Live (Zostavax, Merck) may reduce the risk of subsequent stroke among older adults alongside preventing shingles as well. The researchers noted a 20% reduction in stroke risk in adults under 80 years of age and older adults showed a 10% reduced risk. They noticed reductions in both ischemic and hemorrhagic events. The findings might encourage people age 50 or older to get vaccinated against shingles and to prevent shingles-associated stroke risk.

Feb 20, 2020

Patients with relapsed or refractory large B-cell non-Hodgkin lymphoma can be successfully treated and monitored in the outpatient setting with the chimeric antigen receptor T-cell therapy lisocabtagene maraleucel. The study results showed this approach is feasible even for elderly patients and those with high tumor burden. Infusion and monitoring of patients receiving CAR T-cell therapy in the outpatient setting may lead to wider utilization and improved access.

Feb 14, 2020

The researchers at the university of Virginia School of Medicine have reported that medulloblastoma forms an intricate network to drive its growth. Some tumor cells actually turn into another cell type altogether. Such a discovery raises an exciting possibility that doctors might be able to intervene to fight several types of cancers.

Journal Abstracts

Feb 27, 2020

T.A. Perry et.al. conducted a study to understand if the association between the volumes of Bone marrow lesions subtypes and synovial tissue volume, was present with symptoms in symptomatic knee OsteoArthritis. The researchers concluded that cyst-like component from subchondral Bone marrow lesions was present in cases of knee pain, however these lesions still did not influence any symptoms. 

Feb 26, 2020

Philip J Mease, et.al. conducted a study to compare efficacy and safety of ixekizumab to adalimumab in cases of disease-modifying antirheumatic drug-naïve patients suffering from active psoriatic arthritis and other symptoms. The researchers concluded that ixekizumab was far more superior adalimumab in the achievement of simultaneous improvement of joint and skin disease.

Feb 26, 2020

Chase I. Kahn et.al. conducted a study to assess the evidence available for acupuncture use in otolaryngology. The researchers concluded that since there is a significant safety profile, cost, and perceived benefit- there are increasing recommendations about the use of Accupuncture in this field. However, the real efficacy needs to be evaluated through further studies and trials. 

Recent Articles

Feb 27, 2020

Daniel G. Whitney et.al. conducted a study to determine prevalence of major noncommunicable diseases in young adults with pediatric-onset disabilities and compared it in adults without pediatric onset disabilities. The researchers found that young adults with pediatric onset disabilities showed an early onset of several noncommunicable diseases. They were contributors to global and national burden of disease and mortality.

Feb 27, 2020

Paola Santoro et.al. described two cases of plastic bag suffocation. It is important to know these signs as we often observe that typical signs of asphyxia – petechial haemorrhages, facial congestion, oedema and cyanosis are not present in such cases. Thus to identify these signs the authors studied the data available internationally, and analysed the data available on suicides, homicides and accidental deaths . 

Feb 26, 2020

Philip J Mease, et.al. conducted a study to compare efficacy and safety of ixekizumab to adalimumab in cases of disease-modifying antirheumatic drug-naïve patients suffering from active psoriatic arthritis and other symptoms. The researchers concluded that ixekizumab was far more superior adalimumab in the achievement of simultaneous improvement of joint and skin disease.

Clinical Research

Feb 27, 2020

Christopher G. Brennan-Jones et.al. identified specific strategies which have shown effectiveness in reducing workplace noise. These include implementation of stricter legislation and also stress upon the need for training in the proper use of earplugs and earmuffs so as to reduce noise exposure to safe levels. 

Feb 27, 2020

Daniel G. Whitney et.al. conducted a study to determine prevalence of major noncommunicable diseases in young adults with pediatric-onset disabilities and compared it in adults without pediatric onset disabilities. The researchers found that young adults with pediatric onset disabilities showed an early onset of several noncommunicable diseases. They were contributors to global and national burden of disease and mortality.

Jan 31, 2020

This study investigates whether 1) Silver diamine fluoride (SDF) application using Super Floss can arrest and/or reverse initial interproximal caries on primary molars and 2) whether SDF applied with Super Floss is more effective in arresting or remineralizing initial interproximal lesion in comparison to SDF applied without Super Floss or fluoride varnish applied alone.

Jan 31, 2020

This study investigates whether 1) Silver diamine fluoride (SDF) application using Super Floss can arrest and/or reverse initial interproximal caries on primary molars and 2) whether SDF applied with Super Floss is more effective in arresting or remineralizing initial interproximal lesion in comparison to SDF applied without Super Floss or fluoride varnish applied alone.

Jan 31, 2020

This is the first study where BAY1163877 is given to humans. Impact of the study is to evaluate if patients with advanced solid cancers show advanced clinical benefit under the treatment with the pan FGFR inhibitor. Patients (all comers) will receive the study drug treatment in a dose-escalation scheme (no placebo group) to determine the safety, tolerability and maximum tolerated dose (MTD) of BAY1163877.

Jan 31, 2020

The present study will be a randomized trial investigating the impact of e-cigarette device type on reinforcement value and use among current smokers. Current smokers (n=100) will be randomly assigned to either a control group that does not receive an e-cigarette or one of two e-cigarette types: a customizable tank, or a pod. 

Jan 31, 2020

Study to prospectively collect blood and tumor tissue from esophageal cancer patients to identify specific esophageal cancer mutations that can be measured in the blood (cell-free DNA) during the course of treatment as a marker of response and recurrence.

Publications

Jan 29, 2020

This highly respected and frequently cited journal is a prime source of information in the area of fetal and neonatal research. Original papers present research on all aspects of neonatology, fetal medicine and developmental biology. These papers encompass both basic science and clinical research including randomised trials, observational studies and epidemiology.

Jan 29, 2020

Promoting rational therapy within the discipline of cardiology, the American Journal of Cardiovascular Drugs covers all aspects of the treatment of cardiovascular disorders, particularly the place in therapy of newer and established agents. Via a program of reviews and original clinical research articles, the journal addresses major issues relating to treatment of these disorders, including the pharmacology, efficacy and adverse effects of the major classes of drugs; information on newly developed drugs and drug classes. 

Jan 29, 2020

Journal of Diabetes Investigation is the core diabetes journal from Asia; the official journal of the Asian Association for the Study of Diabetes. The journal publishes original research, country reports, commentaries, reviews, mini-reviews, case reports, letters, as well as editorials and news. The Journal of Diabetes Investigation includes aspects of prevention, treatment, as well as molecular aspects and pathophysiology.

Jan 29, 2020

Hepatobiliary Surgery and Nutrition focuses on new findings in hepatopancreatobiliary disease and nutrition, and to provide current and practical information on diagnosis, prevention and clinical investigations. Specific areas of interest include, but not limited to, surgical techniques, clinical and basic researches, transplantation and other therapies, NASH, NAFLD, targeted drug, gut microbiota, metabolism, cancer immunity, genomics, nutrition and dietetics, etc.

Jan 29, 2020

 

Applied Radiology publishes recent researchers, articles, abstracts, dialogues and discussions on Radiology. The articles are based on current concepts, studies as well as new breakthroughs in technology. Applied Radiology welcomes clinical review articles and radiological cases for publication.

Jan 28, 2020

This book offers a comprehensive overview of all major pathologic conditions involving the lung and mediastinum and the related diagnostic procedures. Oncologic and non-oncologic conditions are reviewed and described in detail, featuring, besides normal anatomy, also high-quality images from several modalities (including X-ray, CT, MR, and PET), as well as b/w and color illustrations and line drawings. Complications associated with surgical and oncological treatments are also presented in detail with extensive imaging examples.

Jan 28, 2020

This book presents a comprehensive overview of recent clinical techniques and findings regarding wounds in burns, infections of wounds, and wound management in general. With the help of numerous high-quality illustrations, the first part of the book describes various approaches to treating patients with burn wounds. In turn, the second part focuses on infections of wounds. Here, the chapter authors summarize the most recent treatment options for wound infection in both children and adults. The third and last part addresses wound management in general, rounding out the content.

Videos

Jan 30, 2020

Dr. Patrick Kamath presented a talk on liver in cases of Cardiac diseases. The speaker has discussed in detail about its symptomatolgy, progression of symptoms, identification of diagnostic signs, recommended investigations and lastly current updates in the treatment strategies of the same. 

Jan 30, 2020

Ashley E. Ross, MD, PhD, Executive Medical Director of the Mary Crowley Cancer Research Center in Dallas, discusses the current and potential impact of PSMA PET imaging on the identification and treatment of localized prostate cancer. He notes how PET PSMA and fluciclovine imaging can increase the accuracy of detecting clinically significant localized disease. Dr. Ross further discusses how PET imaging assists in risk stratification of candidates for treatment of HSPC, nmCRPC using salvage local therapy, metastasis-directed therapy, or intensification of systemic therapy. He also discusses how PET imaging can help identify candidates for cure with local treatments.

Jan 30, 2020

Ashley E. Ross, MD, PhD, Executive Medical Director of the Mary Crowley Cancer Research Center in Dallas, discusses the current and potential impact of PSMA PET imaging on the identification and treatment of localized prostate cancer. He notes how PET PSMA and fluciclovine imaging can increase the accuracy of detecting clinically significant localized disease. Dr. Ross further discusses how PET imaging assists in risk stratification of candidates for treatment of HSPC, nmCRPC using salvage local therapy, metastasis-directed therapy, or intensification of systemic therapy. He also discusses how PET imaging can help identify candidates for cure with local treatments.

Jan 30, 2020

Sasikumar Kilaikode et.al. presented a talk on Neuromuscular Disorders in children with a perspective of Pulmonology with an objective to discuss respiratory patholophysilogy of neuromuscular disease in children, outlining the monitoring of pulmonary features and discussing the management of chronic respiratory failure in children with neuro-muscular disorders in children. 

Case Studies

Feb 26, 2020

Isabella Aquila et.al. describe a case of Sudden death due to Takayasu’s arteritis and how histopathology came in handy by revealing eosinophilia in the aortic wall, consistent with a vasculitis such as Takayasu’s arteritis as the autopsy only showed sclerosis of the thoracic aorta, abdominal aorta and coronary arteries. 

Feb 25, 2020

Shuquan Zhao et.al. presented a case of a a 21-year-old woman diagnosed with “acute gastroenteritis”  who expired 4 days later. Autopsy findings revealed an inflammatory polypous embolic located at 1.0 cm from the left anterior descending branch. To find the real cause of this embolus, virus detection was performed through RT-PCR, however the findings were negative. 

Feb 24, 2020

During a craniotomy, hemostatic materials such as oxidized cellulose and cotton pads, commonly used to control bleeding, may cause a granulomatous reaction that may produce space-occupying mass lesions termed textiloma (or gossypiboma). Nicola Montemurro et al presents the case of a 46-year-old female who underwent a right frontotemporal craniotomy and surgical removal of an intraparenchymal cerebral hemorrhage. The patient developed a textiloma during the postoperative period that led to seizures.

Feb 24, 2020

Follicular lymphoma is an indolent non-Hodgkin lymphoma that is most prevalent among the elderly population. An 82-year-old female with refractory follicular lymphoma achieved a partial response with idelalisib treatment, Despite experiencing two incidences of the psoriasis-like rash during the treatment the patient was able to restart treatment successfully and maintain a continued partial response.