News

Jun 01, 2020

Some women with gestational trophoblastic tumors (GTT), a rare type of cancer that develops in the placenta during pregnancy, respond to immunotherapy when they are resistant to single chemotherapy, French researchers report. The finding comes from the TROPHIMMUN phase 2 trial with the anti-programmed death-ligand 1 (PD-L1) drug avelumab (Bavencio, Merck/Pfizer). The study will be presented at the plenary session of the 2020 American Society of Clinical Oncology (ASCO) Annual Meeting, held virtually because of the pandemic.

Jun 01, 2020

Genetic screening for prostate cancer in GP surgeries could be effective at picking up otherwise undiagnosed cases of the disease, a new pilot study shows. Researchers 'barcoded' men for their genetic risk of prostate cancer by testing each for 130 DNA changes—and gave those at higher risk follow-up checks. Their study found that population screening was safe and feasible, and identified new prostate cancers in over a third of apparently healthy men who were found to have the highest levels of inherited risk.

Jun 01, 2020

Androgen-deprivation therapy (ADT) with an oral gonadotropin-releasing hormone (GnRH) antagonist rapidly suppressed testosterone and cut the incidence of serious heart events compared to an injectable form of ADT, a phase III trial found. The so-called HERO study of over 900 patients met its primary endpoint, demonstrating that castration at 48 weeks was maintained in 96.7% of those assigned to oral relugolix compared to 88.8% of those on leuprolide injection, meeting prespecified criteria for both non-inferiority and superiority (P<0.001), reported Neal Shore, MD, of the Carolina Urologic Research Center in Myrtle Beach, South Carolina.

Journal Abstracts

Jun 01, 2020

Bingqing Ma et.al. conducted a study to explore the risk factors associated with second primary cancer and provide an individualized risk prediction model for Lung cancer patients. The researchers concluded that consideration should be given to increasing the duration of routine follow-up even after 10 years of initial diagnosis for those at the highest risk and site-specific follow-up strategy is also required.

Jun 01, 2020

Shiby Paul et.al. conducted a study to explore dosimetric predictors of activity decline in a cohort of patients who underwent continuous activity monitoring during definitive concurrent chemoradiotherapy for locally advanced lung cancer. The researchers concluded that Extent of cardiac irradiation is associated with the rate of physical activity decline during chemoradiotherapy for lung cancer.

Jun 01, 2020

Lucas Resende Salgado et.al. conducted a study to to determine whether biologic subtype is predictive of local control in breast cancer patients with Brain metastases treated with stereotactic radiosurgery. The researchers concluded that consideration of radiation treatment intensification or altered fractionation to improve local control may be indicated for the TN subtype. Further multicenter studies are necessary to corroborate the results.

Recent Articles

Jun 01, 2020

This research study is being done to understand how patients with chronic cancer pain take their long-acting opioid medications and to develop an intervention to enhance cancer pain management.

Jun 01, 2020

Advance in Cancer Prevention addresses all types of cancer, how cancer forms in the body, and their prevention. It focuses on Cancer Vaccines, Chemotherapy, Radioactive Iodine Therapy, Breast Reconstruction Surgery, Mammography, Chemoprevention, aromatase inhibitors, Scintimammography, Oncoplastic surgery, Sumoylation, Dietary Supplements, Cancer Screening, Cancer and Nutrition, Exercise and Cancer, Alternative Cancer Medicines, Stem cell transplants for cancer prevention, Naturopathic Treatments, Clinical Naturopathy, Cancer Prevention from nuts.

Jun 01, 2020

Rimma Shaposhnikov, MD UCLA gastroenterologist and Natalie Manitius, MPH, RDN, UCLA GI Dietitian, discuss which screening modalities work for colon cancer, how often one needs to get screened when a person can stop colonoscopies and dietary tips to prevent colon cancer.

Clinical Research

Jun 01, 2020

The purpose of this study is to find the most effective dose of radiation therapy to give to breast tumors in a shorter period of time, prior to standard partial mastectomy/axillary surgery.

Jun 01, 2020

This research study is being done to understand how patients with chronic cancer pain take their long-acting opioid medications and to develop an intervention to enhance cancer pain management.

Feb 27, 2020

Christopher G. Brennan-Jones et.al. identified specific strategies which have shown effectiveness in reducing workplace noise. These include implementation of stricter legislation and also stress upon the need for training in the proper use of earplugs and earmuffs so as to reduce noise exposure to safe levels. 

Feb 27, 2020

Christopher G. Brennan-Jones et.al. identified specific strategies which have shown effectiveness in reducing workplace noise. These include implementation of stricter legislation and also stress upon the need for training in the proper use of earplugs and earmuffs so as to reduce noise exposure to safe levels. 

Feb 27, 2020

Daniel G. Whitney et.al. conducted a study to determine prevalence of major noncommunicable diseases in young adults with pediatric-onset disabilities and compared it in adults without pediatric onset disabilities. The researchers found that young adults with pediatric onset disabilities showed an early onset of several noncommunicable diseases. They were contributors to global and national burden of disease and mortality.

Jan 31, 2020

This is the first study where BAY1163877 is given to humans. Impact of the study is to evaluate if patients with advanced solid cancers show advanced clinical benefit under the treatment with the pan FGFR inhibitor. Patients (all comers) will receive the study drug treatment in a dose-escalation scheme (no placebo group) to determine the safety, tolerability and maximum tolerated dose (MTD) of BAY1163877.

Jan 31, 2020

The present study will be a randomized trial investigating the impact of e-cigarette device type on reinforcement value and use among current smokers. Current smokers (n=100) will be randomly assigned to either a control group that does not receive an e-cigarette or one of two e-cigarette types: a customizable tank, or a pod. 

Publications

Jun 01, 2020

Advance in Cancer Prevention addresses all types of cancer, how cancer forms in the body, and their prevention. It focuses on Cancer Vaccines, Chemotherapy, Radioactive Iodine Therapy, Breast Reconstruction Surgery, Mammography, Chemoprevention, aromatase inhibitors, Scintimammography, Oncoplastic surgery, Sumoylation, Dietary Supplements, Cancer Screening, Cancer and Nutrition, Exercise and Cancer, Alternative Cancer Medicines, Stem cell transplants for cancer prevention, Naturopathic Treatments, Clinical Naturopathy, Cancer Prevention from nuts.

Jan 29, 2020

This highly respected and frequently cited journal is a prime source of information in the area of fetal and neonatal research. Original papers present research on all aspects of neonatology, fetal medicine and developmental biology. These papers encompass both basic science and clinical research including randomised trials, observational studies and epidemiology.

Jan 29, 2020

Promoting rational therapy within the discipline of cardiology, the American Journal of Cardiovascular Drugs covers all aspects of the treatment of cardiovascular disorders, particularly the place in therapy of newer and established agents. Via a program of reviews and original clinical research articles, the journal addresses major issues relating to treatment of these disorders, including the pharmacology, efficacy and adverse effects of the major classes of drugs; information on newly developed drugs and drug classes. 

Jan 29, 2020

Journal of Diabetes Investigation is the core diabetes journal from Asia; the official journal of the Asian Association for the Study of Diabetes. The journal publishes original research, country reports, commentaries, reviews, mini-reviews, case reports, letters, as well as editorials and news. The Journal of Diabetes Investigation includes aspects of prevention, treatment, as well as molecular aspects and pathophysiology.

Jan 29, 2020

Hepatobiliary Surgery and Nutrition focuses on new findings in hepatopancreatobiliary disease and nutrition, and to provide current and practical information on diagnosis, prevention and clinical investigations. Specific areas of interest include, but not limited to, surgical techniques, clinical and basic researches, transplantation and other therapies, NASH, NAFLD, targeted drug, gut microbiota, metabolism, cancer immunity, genomics, nutrition and dietetics, etc.

Jan 29, 2020

 

Applied Radiology publishes recent researchers, articles, abstracts, dialogues and discussions on Radiology. The articles are based on current concepts, studies as well as new breakthroughs in technology. Applied Radiology welcomes clinical review articles and radiological cases for publication.

Jan 28, 2020

The Bone Book: An Orthopedic Pocket Manual is a complete guide to the essentials of orthopedics in today's busy hospital and outpatient settings. Concise chapters provide the basic knowledge that all orthopedic surgery residents, medical students, and supporting staff must know to handle the full range of conditions, injuries, and diseases for patients in the operating room and emergency department. 

Videos

Jun 01, 2020

Rimma Shaposhnikov, MD UCLA gastroenterologist and Natalie Manitius, MPH, RDN, UCLA GI Dietitian, discuss which screening modalities work for colon cancer, how often one needs to get screened when a person can stop colonoscopies and dietary tips to prevent colon cancer.

May 27, 2020

Dr. Gonzalo Sapisochin presents his research using living liver transplantation as a treatment for patients with colorectal cancer that has spread to the liver. Liver transplantation is frequently used as a curative treatment for selected patients with the most common liver cancer, hepatocellular carcinoma. Dr. Sapisochin’s study is expanding liver transplantation to patients with colorectal cancer which has spread to the liver. Colorectal cancer is diagnosed in 1.8 million people every year and it is estimated that in approximately 50 percent of these cases, cancer will spread to the liver. "We think that pre-transplant chemotherapy, careful monitoring of tumors, and living donation will give our patients better results," says Dr. Sapisochin.

Jan 30, 2020

Ashley E. Ross, MD, PhD, Executive Medical Director of the Mary Crowley Cancer Research Center in Dallas, discusses the current and potential impact of PSMA PET imaging on the identification and treatment of localized prostate cancer. He notes how PET PSMA and fluciclovine imaging can increase the accuracy of detecting clinically significant localized disease. Dr. Ross further discusses how PET imaging assists in risk stratification of candidates for treatment of HSPC, nmCRPC using salvage local therapy, metastasis-directed therapy, or intensification of systemic therapy. He also discusses how PET imaging can help identify candidates for cure with local treatments.

Jan 30, 2020

Ashley E. Ross, MD, PhD, Executive Medical Director of the Mary Crowley Cancer Research Center in Dallas, discusses the current and potential impact of PSMA PET imaging on the identification and treatment of localized prostate cancer. He notes how PET PSMA and fluciclovine imaging can increase the accuracy of detecting clinically significant localized disease. Dr. Ross further discusses how PET imaging assists in risk stratification of candidates for treatment of HSPC, nmCRPC using salvage local therapy, metastasis-directed therapy, or intensification of systemic therapy. He also discusses how PET imaging can help identify candidates for cure with local treatments.

Case Studies

Feb 26, 2020

Isabella Aquila et.al. describe a case of Sudden death due to Takayasu’s arteritis and how histopathology came in handy by revealing eosinophilia in the aortic wall, consistent with a vasculitis such as Takayasu’s arteritis as the autopsy only showed sclerosis of the thoracic aorta, abdominal aorta and coronary arteries. 

Feb 25, 2020

Shuquan Zhao et.al. presented a case of a a 21-year-old woman diagnosed with “acute gastroenteritis”  who expired 4 days later. Autopsy findings revealed an inflammatory polypous embolic located at 1.0 cm from the left anterior descending branch. To find the real cause of this embolus, virus detection was performed through RT-PCR, however the findings were negative. 

Feb 24, 2020

During a craniotomy, hemostatic materials such as oxidized cellulose and cotton pads, commonly used to control bleeding, may cause a granulomatous reaction that may produce space-occupying mass lesions termed textiloma (or gossypiboma). Nicola Montemurro et al presents the case of a 46-year-old female who underwent a right frontotemporal craniotomy and surgical removal of an intraparenchymal cerebral hemorrhage. The patient developed a textiloma during the postoperative period that led to seizures.

Feb 24, 2020

Follicular lymphoma is an indolent non-Hodgkin lymphoma that is most prevalent among the elderly population. An 82-year-old female with refractory follicular lymphoma achieved a partial response with idelalisib treatment, Despite experiencing two incidences of the psoriasis-like rash during the treatment the patient was able to restart treatment successfully and maintain a continued partial response.