Extrapontine Myelinolysis following Extreme Hypernatremia and Hyperosmolarity

Case Reports in Pediatrics
18 Jan, 2019 ,

A 2-year-and-8-month-old-girl came c/o fever of 38.8°C, vomiting, and refusal to eat for 3 days. Investigations revealed severe hypernatremia and stress hypergylcemia. Isotonic glucose-electrolyte infusion was initiated, MRI of the head showed vague, nonischemic diffusion impairment in the basal ganglia, corpus callosum, and subcortical regions on both sides. CSF Examination was normal. CK was elevated but without any symptoms. The patient recovered and the MRI findings were then thought to be extrapontine myelinolysis following extreme hypernatremia.