Retroperitoneal Angioleiomyomatosis

The Journal of Obstetrics and Gynecology of India
13 Jan, 2021 ,

Luz Angela Torres-de la Roche et al. report the resection of a retroperitoneal angio-leiomyoma in a 35-year-old female by employing a combination of laparoscopy, micro-surgical techniques and endoscopic tools. The patient presented with chronic leg pain and ultrasound and MRT revealed a mucinous cystadenoma of the left ovary. A complete resection of the retroperitoneal tumor was achieved by combining laparoscopic route, in-bag morcellation and micro-surgical techniques.

Source
Full content

A 35-year-old patient with two children underwent laparoscopic retroperitoneal pelvic tumor excision at the Dubai London Clinic and Speciality Hospital. The patient presented with chronic left leg pain for many years.

At admission, ultrasound examination and MRT image findings were described as a mucinous cystadenoma of the left ovary (9.2 × 5.6 cm with relative irregular outline and filling the pouch of Douglas), with the differential diagnosis of a broad ligament leiomyoma with intrinsic tumor degeneration and necrotic features.

By combining laparoscopic route, in-bag morcellation and micro-surgical techniques, it was possible to ensure complete resection of the retroperitoneal tumor without intraoperative vascular or neural complications. At histological examination, the cytology of peritoneal fluid showed mild subacute inflammation with activated mesothelial cells, suggestive of exudative peritoneal effusion. Sections of the soft tissue neoplasm consisted of cellular sheets and irregular fascicles spindled cells with formation of glomeruloid architecture and epithelioid features. The lesion demonstrated numerous anastomosing structures resembling blood vessels covered by endothelium-like cells embedded in fibrous stroma. No evidence of malignancy or tumor necrosis was reported. The tumor was positive for immunomarkers CD31, CD34, D2-40, CD68, Ki-67 (1–2% positive nuclear staining) as well for smooth muscle markers SMA (Smooth muscle actin) and Desmine. HHV-8, S100, Synaptophysin and Calretinin were negative. The postoperative course was uneventful.