Delirium Prevention With Ketamine in Ear, Nose, and Throat (ENT) Patients

ClinicalTrials.gov
14 Nov, 2019 ,

The goal of this prospective randomized double-blinded placebo-controlled study is to investigate if a single dose of ketamine in addition to standard anesthesia will reduce the risk of delirium in otolaryngeal cancer patients postoperatively. Participants will be randomized to one of three groups after administration of general anesthesia; one dose of .5 mg/kg intravenous (IV) Ketamine, 1.0 mg/kg of IV Ketamine, or IV placebo. Ketamine's effect on postoperative pain and opioid use will be measured as well. Electroencephalogram (EEG) will be utilized during the surgical procedure to evaluate its potential as a possible predictive device for delirium.

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