NIH Clinical Trials
The purpose of this study is to find the most effective dose of radiation therapy to give to breast tumors in a shorter period of time, prior to standard partial mastectomy/axillary surgery.
Experimental: Preoperative SABER
- Experimental: Preoperative Stereotactic Ablative Breast Radiotherapy (SABER). Phase I study testing up to 4 dose levels.
- Non-experimental: Participants will undergo standard partial mastectomy and axillary surgery as per the discretion of treating physicians 4 to 6 weeks (+ at most 1-week delay) after preoperative SABER is completed.