SABER Study for Selected Early Stage Breast Cancer (SABER)

NIH Clinical Trials
01 Jun, 2020 ,

The purpose of this study is to find the most effective dose of radiation therapy to give to breast tumors in a shorter period of time, prior to standard partial mastectomy/axillary surgery.

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Experimental: Preoperative SABER

  • Experimental: Preoperative Stereotactic Ablative Breast Radiotherapy (SABER). Phase I study testing up to 4 dose levels.
  • Non-experimental: Participants will undergo standard partial mastectomy and axillary surgery as per the discretion of treating physicians 4 to 6 weeks (+ at most 1-week delay) after preoperative SABER is completed.