CD5 Expression Correlates with Inferior Survival and Enhances the Negative Effect of p53 Over Expression in Diffuse Large B‐Cell Lymphoma

Haematological Oncology
22 Jun, 2020 ,

Peiqi Zhao et.al. conducted a study to assess CD5+ diffuse large B‐cell lymphoma that occurs at a low frequency (9.2%) as not many studies have been done for them. The researchers found that CD5+ diffuse large B‐cell lymphoma was associated with unfavorable clinicopathologic variables and with inferior survival. CD5+ diffuse large B‐cell lymphoma  has a high frequency of p53 overexpression, and CD5 augments the negative effect of p53 overexpression in diffuse large B‐cell lymphoma.

Source