Research Desk

Apr 19, 2019

A 14-year-old adolescent with short stature and delayed puberty, was admitted in a Paediatric Endocrinology outpatient clinic. His familial target height was on percentile 3–10.  After a careful investigation, he was found to have a 45,X/46,X,idic(Y)(p11.32) mosaicism. 

Apr 19, 2019

A 38-year-old with sickle cell disease-associated Pulmonary hypertension and acute chest syndrome was successfully managed with inhaled and oral pulmonary vasodilators in the setting of persistent elevations in pulmonary vascular resistance leading to acute RV failure and cardiogenic shock. 

Apr 19, 2019

A 35-year-old patient was admitted to endocrinology outpatient department with complaint of pain in the neck. Physical examination revealed 2 cm nodule on the thyroid right lobe. Serum thyroid hormone levels were within normal range. Ultrasonography revealed a 23x15 mm hypoechoic nodule with micro calcifications and cystic areas on the right lobe. 

Apr 19, 2019

 A 63-year-old male with severe iron deficiency anemia on biweekly intravenous iron infusions and weekly packed red blood cell transfusions presented with melena over several months. Upper endoscopy demonstrated a clean-based gastric body ulcer and nonbleeding gastric varices. Histology of the gastric ulcer was suggestive of iron-induced gastric mucosal injury.

Apr 19, 2019

 A 51-year-old man came with Rasmussen’s aneurysm that was successfully treated by proximal coil blocking with n-butyl-2-cyanoacrylate (NBCA) injection via the pulmonary artery alone. With proximal coil blocking, a sufficient amount of NBCA could be injected without unintended reflux of the NBCA cast to the proximal pulmonary artery. 

Apr 19, 2019

A new UCLA research suggests that one can save costs for patients and resources of hospitals by eliminating unnecessary procedures before cataract surgery. The researchers added when the doctors did not opt for chest X-rays, electrocardiograms and other preoperative procedures with no significant relation with Cataract surgery- the amount of money saved added up to $67,241 over a period of three years at a medical centre. 

Apr 19, 2019

This multicenter retrospective study is to describe the various presentations and identify predictive factors of death in patients with Calciphylaxis (CPX). Cerium nitrate may lead to vascular decalcification and chelation of reactive oxygen species, and prevent infection. Cerium nitrate-silver sulfadiazine was associated with better outcomes and should be tested in a prospective comparative trial in CPX patients.

Apr 19, 2019

The study aims to report an experience with loop underlay tympanoplasty, a modification of the underlying technique previously reported, for the reconstruction of anterior, subtotal or total tympanic membrane perforations. The loop underlay technique combines the advantages of both underlay and overlay techniques with excellent postoperative outcomes.

Apr 19, 2019

A prospective, longitudinal, descriptive study was conducted from January 2016 to January 2018 to detect nerve dysfunction after hip arthroscopy. A total of 110 patients were included.  Twenty-four hours after surgery, 62.7% reported symptoms of abnormal sensation at least in one area. Nerve dysfunction after HA was more common than has been reported in the literature within large populations. Traction time was a significant factor in the development of perineal nerve dysfunction.

Apr 19, 2019

Here Bronte, et al. retrospectively analyzed ER, PgR, and AR expression on a case series of 159 specimens of primary BC samples by using immunohistochemistry and 89 patients of these had luminal tumors for which AR and ER expression and survival data were available. For twenty-four patients both primary and metastatic tumors were available.  In conclusion, these findings indicate that a prospective study is needed to better clarify the role of AR/ER ratio in different BC settings (i.e., adjuvant and metastatic). The relation between AR and PgR has to be better understood even if our findings suggest that a high AR/PgR ratio in luminal tumors is prognostically unfavorable and could be used as an additional risk-stratification marker.