By Using sound vibrations and pulses of near-infrared light, a Rutgers University scientist has developed a new "virtual biopsy" device that can quickly determine a skin lesion's depth and potential malignancy without using a scalpel. The first-of-its-kind experimental procedure, called vibrational optical coherence tomography (VOCT), creates a 3-D map of the legion's width and depth under the skin with a tiny laser diode.
Using a new blood test that's in development researchers identified characteristics that could be used to personalize treatment for patients with a type of head and neck cancer linked to HPV infection. The researchers developed the test to detect levels of DNA in the blood from HPV-linked oropharyngeal squamous cell carcinoma tumors. Studies are ongoing to see if the test can be used to monitor patients' response to treatment with radiation and chemotherapy.
In a recent meta-analysis of 24 studies, Boone and a team of researchers considered 313 cases of borderline resectable pancreatic cancer that physicians treated with FOLFIRINOX. They analyzed the patients' overall survival rates. They also evaluated how frequently tumors shrank enough to be surgically removed. The team found that FOLFIRINOX prolonged patients' lives, on average, and made surgery possible in more instances.
A hair-sized probe that can measure key indicators of tissue damage deep in the lung has been developed by scientists. A team of scientists developed the probe, which comprises an optical fiber about 0.2mm in diameter that holds 19 sensors. Each sensor can measure different indicators in tissues, such as acidity and oxygen levels, which provide important information on the body's reaction to disease processes.
The results of a pilot study suggest that electrostimulation of one of the nerves connecting the brain to the body (the vagus nerve), could provide a novel treatment approach for patients with rheumatoid arthritis. In this study, a novel miniaturized neurostimulator called a MicroRegulator was implanted into 14 patients with rheumatoid arthritis who had failed on at least two biologics or targeted oral therapies with different mechanisms of action. Patients were randomized to three groups who were either placebo, stimulated once daily, or stimulated four times a day for 12 weeks. At the end of the study, the patients who received once-daily stimulation were shown to have a better response than those on four-times-daily stimulation.
This book presents original articles that report on new approaches and developments involving pulmonary disorders. Pulmonary health attracts public concern as lungs are the first line of defense of the organism against various contagious and are directly influenced by all too often unhealthy constituents of ambient air, which make them vulnerable to diseases. The articles deal with the pathogenic background and most relevant practical aspects of the widespread pulmonary disorders.
Tina Esposito, chief health information officer at Advocate Aurora Health System believes that 'There is no return on analytics or AI unless someone does something with your findings, with your models'. She further added that the key to success wasn't merely the AI, but a seamless marriage between analytics and operations.
The U.S. FDA proposed a 10-month deadline for e-cigarette companies to submit applications to keep their products on the market in response to a Maryland federal judge's ruling that the agency overstepped its authority by allowing e-cigarettes to stay on the market until 2022. The FDA's proposal comes a month after U.S. District Judge Paul W. Grimm ruled that the agency acted illegally in 2017 when the agency extended deadlines to submit marketing applications, saying the decision defeated the purpose of the Tobacco Control Act by allowing unapproved tobacco products to be made and sold, exacerbating the public health issue of youth vaping.
A new computational method will allow scientists to measure the effects of chronic inflammation on energy availability and effort-based decision-making. The method may yield insights into how chronic, low-grade inflammation contributes to motivational impairments in some cases of depression, schizophrenia, and other medical disorders.
Results of a retrospective cohort study showed that although patients receiving ACEIs and ARBs were more likely to receive vasopressors during surgery than those not taking antihypertensive agents, there were no significant differences in intraoperative or postoperative hypotension or any other morbidities, including acute kidney injury (AKI), between groups.