Instead of waiting until the end of the year for contract expiry with current PBM Express Scripts, Anthem will launch IngenioRx during the second quarter of this year. Due to this PBM Agreement will now terminate on March 1, and the IngenioRx business will begin on March 2. This will in return have a significant impact on improving the quality of healthcare.
The government accountability office uncovered inconsistent and often incomplete reviews early in the process of designating medicines as orphan drugs and recommended “executive action” to fix the system. In some cases, FDA reviewers failed to show they had checked how many patients could be treated by a drug being considered for orphan drug status; instead, they appeared to trust what drugmakers told them.
A team of neuroscientists has performed one of the first studies into the central neural circuits (or higher brain areas) that underlie innate responses to odors. They concluded that the flow of olfactory information from the antennae was first processed by the neurons that projected out of the LH and then by the locally connected neurons.
In Michigan, they pass a ban on using telemedicine to prescribe abortion-inducing medication. State bans on using telemedicine for abortion could affect more than just abortions, as they might set a precedent for banning specific use cases of virtual care.
Researchers have uncovered new information about the underlying mechanisms for gastric cancer. They found that they could stop gastric cells dividing and growing by deleting a particular cell-surface receptor. They targeted a specific Fzd receptor called Fzd7, as this was identified the predominant Wnt receptor responsible for the function of stem cells in the stomach and intestine. They found that deletion of Fzd7 in gastric cells made these cells unable to respond to Wnt signals and they failed to divide and grow.
New research reveals that prescription opioids are commonly used long-term to treat pain in older patients with severe osteoarthritis. The analysis included 358,121 patients with an average age of 74 years. One in six patients used long-term prescription opioids for pain management in the year leading up to total joint replacement, with an average duration of approximately seven months.
According to findings published in Obesity, children and adolescents showed greater long-term reductions in BMI when their response in the first month was quick as compared to those who did not show a quick response. During the 6th month of the study, the initial responders showed a greater percentage of baseline BMI reduction. This research helps in concluding that early response is a good predictor in determining weight loss outcomes.
The American Heart Association now suggests that Non-vitamin K oral anticoagulants are the preferred alternative to warfarin in order to reduce the risk of stroke in cases of AFib. The only exception to their use are cases that have moderate to severe mitral stenosis or an artificial heart valve. Lastly the guidelines also suggest that obese individuals should also lose weight in order to reduce other risks associated with Afib.
A new study suggests that optimism has a positive effect on protecting Type-2 Diabetes in postmenopausal women. Amongst other modifiable factors like diet, weight, researchers add that a positive mindset and optimism should also be stressed upon. The researchers added self-reported cynical hostility not only increases the risk of Diabetes but also puts women at risk for other metabolic syndromes.
A new website by the American Gastroenterological Association has taken an initiative for Women with IBD regarding proper planning and care during pregnancy. This website aims at helping women about managing their condition during the time of conception, carrying the child and giving birth. This is going to be of great help as women with IBD are three times more likely to choose to not have children due to common misconceptions associated with IBD.