Researchers have found that anti-malarial drug artemisinin could help patients with genetic or hereditary hearing loss. They used a zebrafish model to check if the drug could work in hearing loss. They explain that hearing is due to the ability of certain proteins to reach the outer membrane of sensory cells present in the inner ear. They noted that the drug artemisinin can help the inner ear to recognize and transport an important protein to the cell membranes of the specialized cells of the inner ear.
A research team has studied a protein that regulates a gene which is linked to metastasis of malignant melanoma. They discovered that a specific protein, called DDX3X, regulates the gene that is central to the development of the pigment cells in the skin. The gene is called MITF. The patient's level of DDX3X can therefore now serve as a biomarker for predicting how intractable the disease will be.
Researchers have developed a prototype mini MRI scanner that fits around a patient's leg. The team says the device - which uses a so-called 'magic angle' effect - could potentially help diagnose knee injuries more quickly, and more accurately. The scientists say the device (which looks like a large metal ring through which a patient places their leg) could help diagnose conditions such as anterior cruciate ligament injuries - particularly common among footballers.
Researchers suggest a possible cell-based therapy to stimulate lung development in fragile premature infants who suffer from a rare condition called Bronchopulmonary Dysplasia (BPD), which in the most severe cases can lead to lifelong breathing problems and even death. They studied genetic signatures in donated human neonatal lungs by using single-cell RNA sequencing analysis. They also performed extensive laboratory tests on mouse models of BPD, including computer-assisted bioinformatics analysis.
The recent recall of nearly two dozen drugs manufactured by Premier Pharmacy Labs reinforces the importance of the newly updated compounding regulations. But compounding experts worry it may stifle development in an already precarious supply chain. The recall follows recent updates to compounding regulations over sterile preparations as well as nonsterile products, radiopharmaceuticals, and hazardous drugs.
On an average hospitals dedicate more than 8.6 million hours of additional labor hours every year to manage drug shortages, a recent survey from Vizient suggested. Survey respondents were 365 Vizient members from acute and non-acute care facilities from the country.
Andrew Cuomo signed a bill for ending vaccination exemptions based on religious beliefs, the latest attempt to address the growing measles outbreak, the worst the U.S. has experienced in decades. The exemption, which exists in some form in most states, allows parents of schoolchildren to cite their religious beliefs in opting their kids out of required vaccines. Supporters of keeping the religious exemptions say religious freedom should not be overpowered by state laws.
According to the new findings discussed in Healthcare Financial Management Association Annual Conference in Orlando, most patients felt a bigger pinch to their wallets as out-of-pocket costs across all settings of care showed increase in the year 2018. It was further suggested that strategies to maximise reimbursements should be implemented in order to encourage patients to opt for healthcare services without worrying about the financial aspect.
Researchers at Oregon Health & Science University (OHSU) found significant differences in the microbiota between boys and girls. The primary microbial genera associated with caries in young children were found in much higher prevalence in caries-active girls than boys.
Fawaz Al Ammary, MD, Ph.D., of Johns Hopkins University in Baltimore, and colleagues concluded from a study that older living kidney donors with hypertension may be at increased risk of developing kidney failure themselves.