Research Desk

Nov 28, 2020

Dagmar Grob et.al. conducted a retrospective analysis to compare nodule enhancement on subtraction CT iodine maps to that on dual-energy CT iodine maps. For the analysis, datasets of lung subtraction and dual-energy CT maps from 30 patients with 95 solid pulmonary nodules were used and it was seen that nodule enhancement at subtraction CT was “highly visible”. From the comparison, it could be inferred that subtraction CT is superior to dual-energy CT in depicting iodine enhancement in pulmonary nodules.

Nov 26, 2020

Javier Collada-Carrasco et.al. conducted a study to analyse the impact of active external and built-in humidifiers on the performance of home ventilators, focusing on their pressurization efficacy and their behaviour under different inspiratory efforts. The researchers concluded that these results indicate the need to monitor pressure changes in the use of external humidification devices in some home NIV ventilators.

Nov 26, 2020

Alex Straumann et.al. conducted a double-blind trial on 204 adults with eosinophilic esophagitis to determine whether budesonide is effective in maintaining the remission of the disease achieved by the administration of the same drug. The study also compared the efficacy of 2 dosages of the drug, 0.5 mg twice daily and 1.0 mg twice daily. Persistent remission was observed in 73.5% and 75% of patients in the 0.5 mg and 1.0 mg groups respectively indicating the higher efficacy of the drug in maintaining remission.

Nov 25, 2020

Flaminia Campo et.al. conducted a study to evaluate the accuracy of preoperative evaluation of vocal fold leukoplakia with Narrow band imaging endoscopy in comparison with histology. The researchers concluded that narrow band imaging can help otolaryngologists in the decision-making process on the necessity to perform a biopsy and transoral surgery or long-term follow-up. 

Nov 24, 2020

Markus Moehler et.al. conducted a study to investigate avelumab (anti–programmed death ligand-1 [PD-L1]) maintenance after first-line induction chemotherapy for gastric or gastroesophageal junction cancer. The researchers concluded that JAVELIN Gastric 100 did not demonstrate superior over all survival with avelumab maintenance versus continued chemotherapy in patients with advanced gastric or gastroesophageal junction cancer overall or in a prespecified PD-L1–positive population.

Nov 24, 2020

The meta-analysis performed by Yan-Li Yang et.al. attempts to determine the effect of β-blockers (BBs) on respiratory function in patients with COPD with cardiovascular disease (CVD), and also compare the effects of cardioselective and noncardioselective BBs. The meta-analysis included data from 49 studies of which 12 were randomized control trials and 37 were observational. Yan-Li Yang et.al. found that BBs reduce all-cause and in-hospital mortality in patients with COPD in addition to reducing the heart rate acceleration caused by bronchodilators. Cardioselective BBs were also found to be helpful in bringing down chronic obstructive pulmonary disease exacerbations.

Nov 24, 2020

A. Reshad Garan et.al. conducted a study to determine whether obtaining hemodynamic data from early pulmonary artery catheter (PAC) placement would positively impact the outcomes in cardiogenic shock (CS). The analysis was based on PAC use prior to initiating mechanical circulatory support (MCS). It was found that a complete PAC resulted in lowest in-hospital mortality and having no PAC done is associated with higher in-hospital mortality. Thus it could be concluded that hemodynamic data obtained via a complete PAC prior to MCS is beneficial in improving survival in CS.

Nov 23, 2020

Durre Sadaf et.al. conducted a study to evaluate the effect of intracanal cryotherapy on postoperative pain after root canal therapy in patients with pulpal or periradicular pathosis. The researchers concluded that moderate-quality evidence suggests that intracanal cryotherapy (ie, using cold saline irrigation as a final irrigant) significantly reduces the intensity of pain at 6 and 24 hours after root canal therapy

Nov 23, 2020

Giuseppe Gregori et.al. carried out a retrospective study to determine if lung ultrasound (LUS) was able to identify typical interstitial lung lesions in children with persistent cough and suspected COVID 19. The analysis was done on 32 children who underwent clinical examination, oximetry measurement and LUS. From the results of the study, it could be concluded that LUS is an effective means to detect lung injury in an outpatient set up and also where there is limited access to medical resources.

Nov 21, 2020

Frisch et,al. conducted a study to compare the short-term outcomes after total hip arthroplasty and total knee arthroplasty between the Veterans Affairs cohort and the general cohort. The researchers concluded that despite controlling for higher rates of medical comorbidities, Veterans Affairs patients undergoing primary total hip arthroplasty and total knee arthroplasty had poorer short-term outcomes than the civilian cohort.