Research Desk

Aug 21, 2019

Ayaka Fujita et.al. conducted a study to investigate pediatrician awareness of and actual circumstances involved in bereavement care in Japan and concluded that Japanese pediatricians provided bereavement care to families who lost their children in a non‐systematic manner and it calls for improvement of the self‐care of health‐care professionals. 

Aug 21, 2019

Dynamic strength training leads to significantly greater improvements in peripheral muscle strength and power output in patients with cardiovascular disease. Dominique Hansen et.al. conducted a systematic review to discuss this line of evidence, which is in contrast to current clinical practice, and to re-open the debate as to what dynamic strength training intensities should actually be applied. 

Aug 21, 2019

 Katrine Hygum et.al. conducted a study to compare diurnal variation in bone turnover in patients with diabetes and controls and concluded that the diurnal variation in bone formation is attenuated in patients with type 2 diabetes and is not explained by changes in incretin hormone levels, but possibly mediated by sclerostin.

Aug 21, 2019

Kruger et.al. conducted a study to determine the impact of Clostridium difficile infections in cirrhosis by evaluating trends and outcomes of early readmission and mortality and concluded that  One-third of Clostridium difficile infections patients with cirrhosis were readmitted within 30-days and it was because of recurrence of infection. 

Aug 21, 2019

Mahsa Kamali et.al. conducted a study to determine the proportion of diagnostic computed tomography colonography (CTC) Reporting and Data System categories in a non-screening population and concluded that older age is increasingly associated with a positive test, a non-diagnostic test and potentially relevant ECF.

Aug 21, 2019

 

Marko Mrkobrada et al evaluated 1,114 patients aged 65 years or older who underwent inpatient, elective, non-cardiac surgery and had brain MRI following surgery—experts examined the association between perioperative covert stroke and cognitive decline 1 year following surgery. Perioperative covert stroke was related to an increased risk of cognitive decline 1 year following non-cardiac surgery, and perioperative covert stroke happened in 1 in 14 patients aged 65 years and older who underwent non-cardiac surgery.

Aug 21, 2019

Lyubomyr M. Lytvynchuk et al reported the rate and management of intra- and early postoperative complications of bag-in-the-lens intraocular lens (IOL) implantation technique for cataract treatment. According to this retrospective non-randomized observational consecutive case series single-centre study, vitreous prolapse and anterior capsule rupture were the most common intraoperative events with 28.9% and 13.3%, respectively. A relatively low rate of intra and postoperative complications, including rare cases of visual axis reo-pacification, was linked to the implementation of bag-in-the-lens technique in the treatment of paediatric cataract. During the learning curve, proper management of complications specifically related to the bag-in-the-lens IOL implantation technique must be considered.

Aug 21, 2019

K. N. Slaughter Wade et al to assess the link between measurements of adiposity (BMI, surface fat area, and visceral fat area [VFA]) and prognosis for oncologic outcomes among patients treated with chemotherapy, with or without bevacizumab (BEV), an anti-angiogenic agent. The ultimate goal was to find whether adiposity interferes with the activity of BEV. Researchers analyzed computed tomography scans taken prior to treatment for 1,538 GOG 218 participants. Findings revealed a strong correlation between measures of adiposity. However, the effectiveness of BEV was not predicted by measures of adiposity. In this study, VFA was identified as a weak prognostic factor.

 

Aug 21, 2019

Prof Kristian Reich, MD et al compared the efficiency and safety of risankizumab with adalimumab in patients with moderate-to-severe plaque psoriasis. In patients with moderate-to-severe plaque psoriasis, risankizumab demonstrated significantly higher efficiency than adalimumab in providing skin clearance. For patients who switched from adalimumab to risankizumab, no additional safety concerns were noted. Moreover, treatment with risankizumab offered flexibility in the long-term treatment of psoriasis.

Aug 21, 2019

Myrela O. Machado, MD et al evaluated the prevalence and odds for depression and anxiety in patients with HS. Of depression, the overall prevalence was 16.9%. Heterogeneity was great. In the subgroup of studies that acknowledged a clinical criteria–based diagnosis of depression, the prevalence of depression was 11.9% vs 26.8% in studies that used a screening instrument. The methodological quality of involved studies moderated those outcomes. In individuals with HS vs individuals without HS, the OR for depression was 1.84. The prevalence of anxiety was 4.9%, and there were inadequate data to ascertain an OR for anxiety in persons with HS since two studies involved a comparison group. Overall, in patients with HS, depression and anxiety were found to be prevalent comorbid conditions.