Research Desk

Jun 04, 2020

K Robin Yabroff et.al. conducted a study to understand how often oncologists discuss costs of testing and treatment or about the factors associated with those discussions as use of genomic testing is increasing in the United States. The researchers concluded that interventions targeting modifiable oncologist and practice factors, such as training in genomic testing and use of electronic medical record alerts, may help improve cost discussions about genomic testing and related treatments.

Jun 03, 2020

Ibiayi Dagogo-Jack et.al. conducted a study to evaluate ALK inhibitor sensitivity in cell lines with MET alterations and assessed antitumor activity of ALK/MET blockade in ALK-positive cell lines and 2 patients with MET-driven resistance. The researchers concluded that treatment with next-generation ALK inhibitors, particularly in the first-line setting, may lead to MET-driven resistance. 

Jun 03, 2020

Katalin Kisivan et.al. conducted a study to investigate time efficiency and target coverage for prostate stereotactic ablative radiotherapy using Triggered Imaging and Auto Beam hold. The researchers concluded that time efficiency of Triggered Imaging + Auto Beam hold with 3 mm/3 sec threshold during prostate stereotactic ablative radiotherapy is comparable with competitive techniques, resulting in minimal 3D residual errors with maintained target coverage.

Jun 03, 2020

Elyamany et.al. conducted a study to assess response to front and second line therapy in patients with Acute Non- Lymphoblastic Leukemia. The researchers concluded that concluded that early blast clearance is a good prognostic factor in Acute Non- Lymphoblastic Leukemia. However patient incompliance was a problem, accordingly efforts has to be exerted to keep patients in regular treatment

Jun 03, 2020

Mehdi Mohammadi Kanesbi et.al. conducted a study to assess the treatment results of Acute Promyelocytic Leukemia as these studies have shown different results. The result of included studies demonstrated that although arsenic trioxide can reduce the number of malignant cells in the bone marrow and peripheral blood, it does not have enough potential to attenuate the danger of high score disseminated intravascular coagulation that is usual in Acute promyelocytic leukemia patients and should be better to be used with other therapeutic methods.

Jun 03, 2020

Elie Rassy et.al. conducted a study to assess the Cancer of unknown primary is an enigmatic disease entity encompassing heterogeneous malignancies without a detectable primary tumour as it is the need of the hour to know the clinical management of Cancer of unknown primary in the era of precision medicine. The published data reveal that the accuracy of site-of-origin predictions made using Cancer of unknown primary classifiers ranges between 54% and 98% when compared with the assignment made according to the recommended clinicopathological criteria.

Jun 03, 2020

Elie Rassy et.al. conducted a study to assess the Cancer of unknown primary is an enigmatic disease entity encompassing heterogeneous malignancies without a detectable primary tumour as it is the need of the hour to know the clinical management of Cancer of unknown primary in the era of precision medicine. The published data reveal that the accuracy of site-of-origin predictions made using Cancer of unknown primary classifiers ranges between 54% and 98% when compared with the assignment made according to the recommended clinicopathological criteria.

Jun 02, 2020

Junjie Li et.al. conducted a study to assess the efficacy and safety of the addition of capecitabine into the triple-negative breast cancer adjuvant treatment regimen was evaluated. The researchers concluded that capecitabine when added to 3 cycles of docetaxel followed by 3 cycles of a 3-drug anthracycline combination containing capecitabine instead of fluorouracil significantly improved DFS in triple-negative breast cancer  without new safety concerns.

Jun 02, 2020

Heiko Schöder et.al. conducted a study to  determine safety and feasibility of PET imaging with 18F-PARPi in patients with head and neck cancer. The researchers concluded that Imaging of head and neck cancer with 18F-PARPi is feasible and safe. 18F-PARPi detects primary and metastatic lesions, and retention in tumors is longer than in healthy tissues.

Jun 02, 2020

Benjin D. Facer et.al. conducted a study to assess the efficacy of Intraoperative radiation therapy using electronic brachytherapy. The researchers concluded that Intraoperative radiation therapy is a convenient and well-tolerated treatment option for the appropriately selected woman undergoing partial breast irradiation. Rates of seroma formation are similar to rates reported for multiple fraction catheter-based systems.