Research Desk

Feb 20, 2019

Trine Apostolaki‐Hansson et al compared 90-day survival and functional outcome following non-Vitamin K Antagonist oral anticoagulants (NOAC)-intracerebral hemorrhage (ICH), the most serious adverse effect of treatment with oral anticoagulants, with vitamin-K antagonists (VKA)-ICH. On the basis of the modified Rankin Scale (mRS), the estimated functional results at 90 days were compared with the ICH associated with VKA and NOAC using a chi-squared test. Participants in the study were 2483 patients (300 with NOAC-ICH and 2183 with VKA-ICH). Increased age and reduced level of consciousness were factors predicting death. No significant difference in mortality and functional outcome at 90 days was observed between NOAC-ICH vs VKA-ICH in this large study on anticoagulant-associated ICH.

Feb 20, 2019

Samantha K. Shirk, DO et al examined the initial hematocrit concentration in preterm births (23-34 weeks) in correlation with delayed clamping vs milking of the umbilical cord. In addition, they compared delayed with milking regarding the incidences of intraventricular hemorrhage, necrotizing enterocolitis, and need for transfusion. Outcomes suggest that to delayed cord clamping, milking the umbilical cord may be an acceptable alternative as it had similar effects on neonatal hematocrit concentrations and need for neonatal transfusions and had no increased risk for complications or neonatal morbidity. Milking of the umbilical cord seems to be an efficient and timely method that can provide increased blood volume to the infant.

Feb 20, 2019

Dr. Yaseen M. Arabi, M.D. et al sought to ascertain the incidence of deep-vein thrombosis among critically ill patients receiving pharmacologic thromboprophylaxis alone vs combined with adjunctive intermittent pneumatic compression. Findings revealed no significant difference in the incidence of proximal lower-limb deep-vein thrombosis between the two methods.

 

Feb 20, 2019

Christopher Plata et al assessed CPR quality in relation to the use of a smartphone application (PocketCPR) in a bystander CPR scenario vs dispatcher-assisted telephone CPR and uninstructed CPR. They used a manikin on whom 8-minute CPR was performed by 100 laypersons. Four groups were defined including randomly assigned volunteers: uninstructed CPR (uninstructed group), dispatcher-assisted telephone CPR (telephone-group), guidance and feedback through a smartphone application (app-group) and dispatcher-assisted telephone CPR combined with the smartphone-app (telephone + app-group). With regard to no-flow-time, compression rate, correct hand position, and thorax release, bystander CPR quality could be improved using feedback by a smartphone application. Also, this strategy did not delay CPR onset. No marked improvement in compression depth was achieved by using a smartphone application.

Feb 20, 2019

A study aimed to determine the predictors of burnout syndrome amongst medical students in Cameroon. 413 medical students were recruited consecutively after sampling three of the five medical schools. It was found that It was found that marital status significantly predicted burnout, as well as relationship difficulties, cumulative GPA, regretting the choice of medical studies, etc. and early detection of burnout in medical students could be done by identifying and addressing the potential determinants.

Feb 20, 2019

A study examined risk factors and outcomes of hospital readmission following complex hepatopancreatobiliary (HPB) surgery among the elderly. It was found that roughly 1 in 7 elderly patients were readmitted within 30 days and 1 in 4 patients within 90 days. Elderly patients with multiple comorbidities were more likely to be readmitted at non-index hospitals.

Feb 20, 2019

A study was conducted to identify biological or clinical variables able to predict or rule out significant pathology on abdominal CT in patients presenting to an emergency department with acute abdominal pain. It revealed that the high specificity of the association between leukocytosis and relative lymphopenia amongst the study population suggests that these parameters would be sufficient to justify an emergency CT. 

Feb 19, 2019

Hyun Woo Goo studied the technical feasibility of semiautomatic 3-D threshold-based cardiac CT quantification of left ventricular mass in patients with various degrees of left ventricular hypertrophy in 99 patients. They concluded that CT quantification is feasible with high reproducibility and the mass values and the ventricular volumes can be used in patients with various degrees of LVH. 

Feb 19, 2019

Oscar Ramirez et.al. studied 1808 patients prospectively in order to describe childhood cancer survival disparities within a universal healthcare system in Cali. They concluded that there were significant disparate survival outcomes, primarily by insurance and tumor type. 

Feb 19, 2019

Terry J Smith et.al. reviewed medical therapies proven capable of altering the clinical outcome of Thyroid-Associated Ophthalmopathy. They concluded that moderate to severe disease showed dramatic and rapid reductions in disease activity with targeting of IGF-IR with specific biologic agents .