The purpose of this study is to observe the effect of obesity on exercise capacity in unilateral diaphragm paralysis (UDP) patients. All obese and nonobese patients with UDP undergoing cardiopulmonary exercise testing (CPET) during a 32-month period in the exercise laboratory of an academic hospital were compared to a retrospectively identified cohort of obese and nonobese controls without UDP, matched for key features. Study results suggest neither UDP nor obesity alone significantly reduced exercise capacity. Superimposed UDP and obesity interact to create a ventilatory limitation to exercise, with reduced peak-VO2, exercise time, and work rate.
This study is to characterize and compare the cutaneous microbiome in 20 healthy controls and 23 patients with psoriasis using metagenomic analyses and to determine changes in the microbiome during treatment. Shifts in the cutaneous microbiome in psoriasis, particularly during treatment, may shed new light on the pathogenesis of the disease and may be clinically exploited to predict treatment response.
This systematic review was conducted to focuses on comparative studies of reconstruction with free flaps (FF) versus pedicled flaps (PF) after oncologic resection. A total of 30 articles were included. The comparison of both types of flaps is limited by the inherent design of the studies included. In sum, FF seems superior to the pectoralis major myocutaneous flap (PMMF) for several outcomes. Submental island flap (SMIF) and supraclavicular artery island flap (SCAIF) compare favorably to FF for some specific indications achieving similar outcomes at a lower cost.
The efficacy of 8% arginine containing prophylaxis products was evaluated over 24 weeks in subjects with dentin hypersensitivity (DH). A significantly greater alleviation of DH was observed in the arginine test group than in the control group at all evaluation appointments.
Between 2010 and March 2018, 35 calcium tartrate stones in 25 patients were identified in the Mayo Clinic database as well as 2 at Baylor Scott & White Health Temple, Texas. The true prevalence of this relatively unknown stone remains unclear and additional investigation is needed.
Chen et.al. conducted a study to evaluate the fecal microbiome of children based on C difficilecolonization, and CDI risk factors, including antibiotic use and comorbid inflammatory bowel disease. They concluded that antibiotic use and IBD status were seen to be present in association with decreased gut bacterial diversity and altered microbiome composition.
J. Eckert et.al. conducted a study to assess the efficacy of CCTA in cases of in-stent-restenosis. They concluded that CCTA proved to be a valuable tool for safely ruling out the possibility of in-stent-restenosis. They also added that the rate of false-negative findings were pretty low.
Sogol Gachkar et.al. conducted a study to understand how thyroid hormones modulate aortic contractility. The researchers concluded that thyroid hormones regulate aortic tone through genomic and non-genomic actions, although genomic actions seem to prevail in vivo.
Lea Fayad et.al. conducted a study to assess the 6-month weight loss outcomes and adverse events of ESG with LSG in a case-matched cohort. They concluded that Endoscopic sleeve gastroplasty (ESG) showed less weight loss at 6 months than laparoscopic sleeve gastrectomy (LSG).
Efren J. Flores et.al. reviewed the accessibility of Lung Cancer screening in cases with a known Mental Illness. The groups with Mental Illnesses show two to four times greater lung cancer mortality and this is majorly attributed to excessive smoking, delay in the diagnosis of cancer as well as treatment.