Research Desk

Jun 17, 2016

Multiple reviews and metaanalyses have tried to estimate CRC risk in patients with IBD and several additional studies were published last year Few of these studies are large prospective populationbased studies which reflect the substantial methodological challenges Here we first outline the criteria for valid studies on IBD and cancer and then use those criteria to critically review the existingstudies

Jun 17, 2016

A study was conducted to evaluate the safety efficacy and feasibility of a minimally invasive vaginal approach for treating advanced uterovaginal prolapse 42 patients were enrolled Combined sacrospinous hysteropexy and cystopexy through a single incision appears to be a safe and efficacious procedure that was relatively easy for surgeons to learn and resulted in a fast postsurgical recovery

Jun 17, 2016

Pediatric patients show higher tendency for visible scars Darkskinned patients are more prone to develop cosmetically significant scars The use of subciliary approach significantly improves the cosmetic outcome and the use of monofilament nonabsorbable sutures for skin closure as prolene 60 is associated with less scar visibility

Jun 17, 2016

Despite very low prevalence of S aureus and MRSA nearly onethird of adults hospitalized with CAP received antiMRSA antibiotics The clinical presentation of MRSA CAP overlapped with pneumococcal CAP highlighting the challenge of accurately targeting empirical antiMRSA antibiotics with currentlyavailable clinical tools and the need for new diagnostic strategies

Jun 17, 2016

The objective of this study was to compare the volumetric IRE ablation zone on greyscale transrectal ultrasoundTRUS contrastenhanced ultrasoundCEUS and multiparametric MRImpMRI with histopathology findings and to determine a reliable imaging modality to visualize the IRE ablation effects accurately mpMRI and CEUS are appropriate for assessing IRE effects and are the most feasible imaging modalities to visualize IRE ablation zone

Jun 17, 2016

The authors hypothesized that an Internet intervention in addition to usual care is superior to care as usual alone CAU in the treatment of mild to moderate depressive symptoms in adults This trial was controlled randomized and assessorblindedThe Internet intervention examined in this trial was superior to CAU alone in reducing mild to moderate depressive symptoms

Jun 17, 2016

The authors aimed to investigate pretreatment neurocognitive performance as a predictor of antidepressant response to tDCS Data was pooled from five clinical trials including two randomised controlled trials RCTs which investigated the antidepressant effects of anodal tDCS administered to the prefrontal cortexBetter pretreatment letter fluency performance measured using the COWAT predicted antidepressant response to tDCS after controlling for confounds

Jun 17, 2016

The authors aimed to determine the association between atopic dermatitis AD and cardiovascular events in the Nurses Health Study 2 a cohort of US women We used logistic regression models to calculate age and multivariateadjusted odds ratios OR and 95 confidence intervals CI for the associations between history of AD and nonfatal MI and nonfatal stroke

Jun 17, 2016

The aim of the study was to determine which atrial fibrillation AF patients should receive anticoagulation therapy clinical treatment guidelines recommend the use of CHADS2 and CHA2DS2VASc riskstratification schemes While the CHADS2 considers congestive heart failure hypertension age 75 years and diabetes mellitus the CHA2DS2VASc also considers gender vascular disease and patients age 6574 years

Jun 16, 2016

When efficacy of inotuzumab ozogamicin an antiCD22 antibody conjugated to calicheamicin in relapsed or refractory acute lymphoblastic leukemia was compared with the standard therapy the rate of complete remission was significantly higher in the test group Both progressionfree and overall survival were longer with inotuzumab ozogamicin Venoocclusive liver disease was a major adverse event associated with inotuzumab ozogamicin