Marcia L Feldkamp et al study involving mothers of 1366 gastroschisis [a severe abdominal defect in which the midgut prolapses outside the abdominal cavity, usually on the right, adjacent to the umbilical cord] cases and 11,238 healthy controls, researchers evaluated the correlation between occurrence and timing of maternal self-reported genitourinary tract infection (urinary tract infections [UTIs] and/or sexually transmitted infection [STI]) and risk for gastroschisis in the offspring. During the periconceptional period (defined as 3 months prior to 3 months after conception), genitourinary infections were frequent in case (19.3%) and control women (9.9%). Investigators found that the risk was highest among women <20 years of age with an STI before conception and in women ≥25 years of age, the risk was comparable for before and after conception. According to findings, UTI and/or STI were related to increased risk of gastroschisis, with association strength varying depending on maternal age and infection timing.
Helen R. Stagg et al evaluated peer support intervention effectiveness in promoting successful clinical engagement with chronic hepatitis C services. Three hundred and sixty-four people agreed to take part. One hundred one suffered from chronic hepatitis C and were randomized, 63 receiving the intervention (peer support). According to this randomized controlled trial, peer support can improve engagement with health care services for patients with chronic hepatitis C virus (HCV). Before implementing them in different healthcare settings, the cost-effectiveness of such interventions in the relevant populations should be assessed. There have been no reported serious adverse events.
Kjellberg, Sigvar et al studied 421 consecutive cases admitted to a stroke unit in order to describe systolic blood pressure development among patients in the acute phase after stroke. They also determined if intensified antihypertensive treatment during this phase is related to the risk of falling within the first 10 days. During the first 2 days of post-acute stroke, systolic blood pressure underwent a spontaneous decline. This attenuation appeared to be present irrespective of stroke type, age, and use of antihypertensive treatment. Intensified antihypertensive treatment during the first 7 days following stroke was not related to falls.
Ricardo Iramain et.al. conducted a study to assess the utility of of salbutamol and ipratropium bromide by MDI versus by Nebulizer in severe asthma exacerbation. The researchers concluded that MDI with valved‐holding chamber and mask along with oxygen by a cannula separately was far more effective than administration through a Nebulizer.
Seung-Whan Lee et.al. conducted a study to assess the efficacy of Percutaneous Coronary Intervention in treating Chronic Total Occlusion. The researchers concluded that PCI was feasible with high success rates and there was no difference in the rate of major adverse events post the procedure.
Athanasios Fountas et.al. conducted a Systematic Review and Meta-Analysis to determine the recurrence rates of silent corticotroph adenomas after primary treatment and the ratio of recurrence between silent corticotroph adenomas with other nonfunctioning pituitary adenoma types. The researchers concluded that there was no supporting evidence for higher recurrence risk in silent corticotroph adenomas when compared to other types.
Lian et.al. conducted a study to assess he performance of γ-glutamyl transpeptidase-to-platelet ratio for diagnosing HBV-related significant fibrosis, severe fibrosis, and cirrhosis. The researchers concluded that moderate diagnostic accuracy for predicting HBV-related significant fibrosis and further studies with larger sample size are required.
Takashi Fujii et.al. conducted a study to assess patency rate of the anterior choroidal artery and the imaging findings in the treatment of patients with intracranial aneurysms. The researchers concluded that in the patients with flow diverter deployment the anterior choroidal artery was patent and there was no ischaemia that was detected on imaging or on examination.
Claudia Tschammler and a team of researchers at the University of Göttingen, Germany set out to analyze the prevalence and severity of erosive tooth wear and caries experience in children and adolescents with overweight, obesity and extreme obesity. They found that higher BMI of children and adolescents is significantly associated with a higher risk for erosive tooth wear and caries.
A team of investigators headed by Hazem Elmansy conducted a study to clarify the key steps and evaluate the early results of the recently introduced top-down holmium laser enucleation of the prostate (HoLEP). They concluded that the top-down method may reduce the complexity, operating time, and the learning curve for urologists performing the HoLEP procedure.