Kapil Sahnan et.al. studied definitive core outcome set for perianal Crohn’s disease as lack of outcomes hampers analysis of data while assessing treatment outcomes. They concluded that application of core outcome set reduced the heterogeneity in outcome reporting and thus helped in meaningful comparisons between mode of treatments, patient care etc.
Yiming Gao et.al. have reviewed normal pattern of nipple enhancement at MRI in healthy individuals with respect to its appearance in healthy individuals and co-related the normal nipple enhancement at MRI with structural anatomy of the nipple at histopathologic analysis, and artifacts and pitfalls related to MRI. As this helps Radiologists to differentiate between normal and abnormal nipple findings thereby providing increased diagnostic efficacy.
The objective of this cross-sectional study was to assess the prevalence of peripheral arterial disease (PAD) in diabetic subjects with foot ulcers in Nigeria. A total of 160 subjects were recruited for this study. Peripheral arterial disease is quite common in diabetic subjects in Nigeria.
This study evaluated the benefits of olanzapine compared with placebo for adult outpatients with anorexia nervosa. Seventy-five participants were assigned to receive olanzapine and 77 to receive placebo. This study documented a modest therapeutic effect of olanzapine compared with placebo on weight in adult outpatients with anorexia nervosa, but no significant benefit for psychological symptoms.
The objective of this study was to estimate the relationship between obstructive sleep apnea (OSA) severity and left ventricular diastolic dysfunction (LVDD) and pentraxin-3 (PTX-3). OSA patients showed significant enhancement of PTX-3 levels and LVDD. Both PTX-3 and LVDD were independently correlated with severity of OSA defined by an apnea-hypopnea index (AHI). Serum PTX-3 levels were positively correlated with LVDD in OSA patients.
A recent study tired determining the difference between ambulatory or home blood pressure monitoring in order to improve diagnosis as well as monitoring of hypertension. The researchers concluded that ambulatory values for day time systolic & diastolic blood pressure differed significantly, and were lower than home values. However the difference between these values was not reproducible for individuals.
A study was conducted to ascertain the potential of plasma steroid hormone profiling through liquid chromatography tandem mass spectrometry in diagnosis of malignancy in adrenocortical tumors. The researchers concluded that application of this analysis helps diagnosis of malignancy in non-expert centers. The positive predictive values were 92 and 96% for Males and Females respectively.
A study was conducted to determine the association between antibiotics during pregnancy or infantile age and very early onset IBD. The researchers concluded that antibiotic exposure during pregnancy and not infantile age was associated with an increased risk of very early onset IBD.
A study was conducted in order to understand the performance and safety of a novel aspiration 6-French AXS Catalyst catheter. during this study, a total number of 60 patients were included, the researchers concluded that Endovascular stroke therapy using the AXS Catalyst catheter seems safe and effective but with no difference in performance than other available catheter options.
A study was conducted to determine the association between statin use at diagnosis and time to progression on active surveillance. The researchers concluded that the use of statin at the time of diagnosis was not significantly protective against any kind of pathological or therapeutic progression in men who undergo active surveillance for Prostate Cancer.