Research Desk

Mar 27, 2019

Nazem Akoum et al examined patients with type 2 diabetes and those with moderate-to-severe CKD who were not on dialysis in order to assess the rates of subclinical arrhythmias in these patient populations. They used continuous ambulatory cardiac monitors for this purpose. Overall, for 11.2±3.9 days, 38 patients underwent ambulatory cardiac monitoring. These patients had a mean eGFR of 38±13 mL/min/1.73 m2. For any cardiac arrhythmia, the estimated overall mean rate was 88.8 episodes/person-year (PY). Episodes of atrial fibrillation occurred at a rate of 37.6/PY. Overall, a common prevalence of cardiac rhythm abnormalities was reported in patients with diabetes and moderate-to-severe CKD not needing dialysis. High rates of atrial fibrillation and asymptomatic episodes were observed in these populations.

 

Mar 26, 2019

A Randomized Control Trial was conducted in order to Efficacy and safety of pregabalin as adjunctive treatment for children showing partial onset seizures. The children included for the study were between 4-16 years of age. The researchers concluded that Pregabalin 10 mg/kg/d  showed reduction in seizure frequency. The doses were safe and well tolerated. 

Mar 26, 2019

Wenzhen Li et.al. conducted a meta-analysis of cohort studies to understand quantitatively the association between parity and cardiovascular disease risk. They concluded that was an association between the number of pregnancies and the risk of cardiovascular disease. 

Mar 26, 2019

Irakoze Laurent et.al. conducted a Meta-Analysis in order to compare the effectiveness of Adrenal venous sampling with ACTH stimulation and Adrenal venous sampling without ACTH stimulation in patients with primary aldosteronism. The researchers concluded that Adrenal venous sampling with ACTH stimulation can significantly reduce the number of unsuccessful cannulations,however further studies are required to verify results. 

Mar 26, 2019

Abdelfatah et.al. conducted a study to o compare the long-term outcome of Endoscopic submucosal dissection versus surgery in early gastric cancer. The researchers performed a systematic and comprehensive search of major reference databases and concluded that Adequate surveillance with upper endoscopy is crucial after Endoscopic submucosal dissection in order to detect early recurrence and metachronous lesions.

Mar 26, 2019

Christian Schoenfeld et.al. conducted a study to measure treatment response after a single balloon pulmonary angioplasty session using cardio-pulmonary MRI. The researchers concluded that Cardio-pulmonary MRI detects and quantifies treatment response after a single BPA treatment session.

Mar 26, 2019

A study in Taiwan aimed to observe whether the pivotal hospitalists care model (HOS) at ED worked functioning with good outcomes for patients care, shortened waiting time for hospitalization, reduced mortality, and increased patient satisfaction compared to previously. It concluded that the first-shot HOS model at ED improved patients care quality, lessened waiting time and mortality, and increased satisfaction.

Mar 26, 2019

Investigators conducted a study to evaluate the desensitizing effect of nano-hydroxyapatite (n-HAP) on dentine hypersensitivity(DH). The n-HAP-containing treatment showed better clinical performance than other treatments for DH relief. However, long-term follow-up RCTs are required in the future before definitive recommendations can be made.

Mar 26, 2019

Stefania Zamboni et al sought to evaluate the role of complete transurethral resection of bladder tumors (c-TURBT) on oncological outcomes after radical cystectomy (RC) and its relationship with adverse pathological features. The findings revealed a low rate of achievement of pT0 stage at RC. An incomplete TURBT before RC represented a predictor of pT3–T4 stages, but no effect of a c-TURBT was shown on survival outcomes.

Mar 26, 2019

A recent study conducted by Lauren V. Moran, M.D et al has revealed that among adolescents and young adults with ADHD who were receiving prescription stimulants, new-onset psychosis occurred in approximately 1 in 660 patients. Amphetamine use was associated with a greater risk of psychosis than methylphenidate.