This study evaluated the benefits of olanzapine compared with placebo for adult outpatients with anorexia nervosa. Seventy-five participants were assigned to receive olanzapine and 77 to receive placebo. This study documented a modest therapeutic effect of olanzapine compared with placebo on weight in adult outpatients with anorexia nervosa, but no significant benefit for psychological symptoms.
The objective of this study was to estimate the relationship between obstructive sleep apnea (OSA) severity and left ventricular diastolic dysfunction (LVDD) and pentraxin-3 (PTX-3). OSA patients showed significant enhancement of PTX-3 levels and LVDD. Both PTX-3 and LVDD were independently correlated with severity of OSA defined by an apnea-hypopnea index (AHI). Serum PTX-3 levels were positively correlated with LVDD in OSA patients.
A recent study tired determining the difference between ambulatory or home blood pressure monitoring in order to improve diagnosis as well as monitoring of hypertension. The researchers concluded that ambulatory values for day time systolic & diastolic blood pressure differed significantly, and were lower than home values. However the difference between these values was not reproducible for individuals.
A study was conducted to ascertain the potential of plasma steroid hormone profiling through liquid chromatography tandem mass spectrometry in diagnosis of malignancy in adrenocortical tumors. The researchers concluded that application of this analysis helps diagnosis of malignancy in non-expert centers. The positive predictive values were 92 and 96% for Males and Females respectively.
A study was conducted to determine the association between antibiotics during pregnancy or infantile age and very early onset IBD. The researchers concluded that antibiotic exposure during pregnancy and not infantile age was associated with an increased risk of very early onset IBD.
A study was conducted in order to understand the performance and safety of a novel aspiration 6-French AXS Catalyst catheter. during this study, a total number of 60 patients were included, the researchers concluded that Endovascular stroke therapy using the AXS Catalyst catheter seems safe and effective but with no difference in performance than other available catheter options.
A study was conducted to find the link between childcare experiences in relation to care instability as well as mother's perceptions regarding childcare access. The researchers also explored mechanisms through which childcare experiences can be used to support maternal mental health. They concluded that increasing care accessibility and awareness of available options for the mental health of mothers are common but have largely been unconsidered. Care instability did not show any direct association with maternal mental health.
A randomized prospective study was conducted to determine the effectiveness of adenoidectomy versus mometasone furoate (MF) nasal spray in the treatment of children with adenoid hypertrophy. Results suggest, in patients were adenoidectomy is contraindicated, long term MF nasal spray treatment has good efficacy in the treatment of nasal obstruction due to adenoid hypertrophy.
This study is to assess the serum concentrations of some factors affecting angiogenesis in patients with rosacea. They studied 72 patients blood samples with type ETR and PPR of rosacea and 21 healthy volunteers were involved in the study. Increased production of proangiogenic factors; VEGF and IL-6 together with reduced antiangiogenic endostatin could be responsible, at least in part, for intensive angiogenesis and erythema in patients with rosacea.
This retrospective study to determined the prognostic factors and utility of allogeneic hematopoietic cell transplantation among children with newly diagnosed hypodiploid acute ALL treated in contemporary clinical trials. Results showed minimal residual disease (MRD) -stratified treatments improved the outcome for children with hypodiploid ALL.