This study is to evaluate the relations between external knee moment and the knee joint movement during stance phase of the patients with knee osteoarthritis (OA). The first peak external knee adduction moment was moderately positively correlated with the maximum knee varus angle at the early stance phase. The peak external knee extension moment at the early stance phase was strongly positively correlated with the knee flexion angle at foot-strike.
This is a qualitative study to identify the lifestyle modification by exploring facilitators that help persons with schizophrenia to adopt the lifestyle modification behaviors and factors that help to adhere to lifestyle modification behaviors. Results suggest individuals with serious mental illnesses such as schizophrenia encounter physical health-related problems, facilitators of lifestyle change behavior help them to adhere to change in their routine life.
- This study aimed to evaluate the potency and effectiveness of oral bambuterol in the management of the disease in fifty patients followed up over 2 weeks with objective assessment of symptom scores and changes in the frequency of rescue bronchodilator after 2 weeks of treatment. Bambuterol 10 mg oral tablet once a day provides significant improvement in pulmonary function tests and effectively reduces asthmatic symptoms.
A systematic review and meta-analysis was conducted in order to determine the diagnostic yield, specimen adequacy, and adverse events associated with EUS-guided Liver Biopsy. This study was conducted in 437 patients. The researchers concluded that EUS-guided LB appears to be both effective and safe as it showed a a histologic diagnosis rate of 93.9% and adverse event rate of 2.3%.
A prospective study was conducted to determine the value of liver fibrosis assessment by ARFI and APRI on patients with common chronic liver diseases in 119 patients with chronic hepatitis B and/or C, alcoholic liver disease and non-alcoholic steatohepatitis. The researchers arrived at a conclusion that increasing Shear wave velocity and APRI correlates with higher degree of liver fibrosis. ARFI was significantly better than APRI in evaluating the degree of liver fibrosis.
A prospective cohort study was conducted in order to assess the trends of blood pressure, blood sugar, body mass index (BMI), and quality of life (QoL) changes in a cohort of patients undergoing pheochromocytoma surgery in order to understand he minimum duration of monitoring and assess factors that could predict these changes. A total of patients undergoing this surgery were evaluated for 20-consecutive months. They concluded that Hypotension was seen in 30% cases, hypoglycemia was seen in 15% cases post-surgery. They also added that Older, diabetic patients are more likely to have persistent HTN.
A systematic review was conducted in order to assess the efficacy of Non-Invasive Ventilation, during travel and support in children aged (0-18 years) requiring critical care transport due to Acute Respiratory Distress for which 1,287 records were identified. The researchers concluded that in-transport adverse event rate for NIV was between 1-4%. The researchers added that well-conducted observational studies are further required.
A study was conducted to assess a metabolic profile associated with circulating Hp and carotid arterial functions via a targeted metabolomics approach to provide insight into potential mechanisms. Total 240 participants were included in the study, significant differences of 19 metabolites and 17 metabolites were seen between Diabetic and Non-Diabetic subjects. The researchers concluded that Targeted metabolomics analyses might be a source of a new insight into the mechanisms regarding the association between serum Hp and carotid arterial functions.
Eric D. Buras et.al. tried determining the extent of diaphragm muscle function impairment by assessing in vivo by ultrasonography and ex vivo by measurement of contractile force in patients on chronic high-fat diet feeding. Their study findings suggest an important role for fibro-adipogenic progenitors-mediated fibro-adipogenic diaphragm remodeling in obesity-associated respiratory dysfunction.
Dr. Han, Yuan, MD, Ph.D. et al investigated whether preoperative screening of salivary cortisol levels may help identify patients at elevated risk for postoperative cognitive dysfunction (POCD). With a sensitivity of 50% and specificity of 91%, 5.69 was identified as the optimal cutoff value. Preoperative salivary cortisol AM/PM ratio could be potentially useful for screening patients for an increased risk.