Research Desk

Mar 26, 2019

Stefania Zamboni et al sought to evaluate the role of complete transurethral resection of bladder tumors (c-TURBT) on oncological outcomes after radical cystectomy (RC) and its relationship with adverse pathological features. The findings revealed a low rate of achievement of pT0 stage at RC. An incomplete TURBT before RC represented a predictor of pT3–T4 stages, but no effect of a c-TURBT was shown on survival outcomes.

Mar 22, 2019

This study is to determine the genetic basis of central centrifugal cicatricial alopecia (CCCA). They used exome sequencing in a group of women with alopecia (discovery set), compared the results with those in a public repository, and applied other filtering criteria to identify candidate genes. Result suggest mutations in PADI3, which encodes a protein that is essential to a proper hair-shaft formation, were associated with CCCA. 

Mar 22, 2019

The aim of this observational, cross-sectional study is to determine the prevalence ratio of otitis media with effusion in laryngopharyngeal reflux. The prevalence ratio of otitis media with effusion in laryngopharyngeal reflux group is 4.5 times that in non-laryngopharyngeal reflux group.


 

Mar 22, 2019

The aim of this study was to examine the prognostic value of the neutrophil-to-lymphocyte ratio (NLR) for patients with advanced gastric cancer receiving second-line chemotherapy. The association of overall survival (OS) in second-line chemotherapy and the clinicopathological findings including NLR were analyzed retrospectively.  Patients with advanced gastric cancer with performance status 2, hemoglobin < 10 g/dL, and NLR before first-line chemotherapy ≥3 are not likely to benefit from second-line chemotherapy.

Mar 22, 2019

This was an observational and retrospective and involved 30 patients to determine the rate of recurrence of this pathology in a series of arthroscopic patients & to assess patient satisfaction well after the operation. The 13% recurrence rate is on the average of what is observed. Later satisfaction with the intervention is very good, and complications remain rare.

 

Mar 22, 2019

The aim of this study was to evaluate the prognostic factors, including the level of N1  lymph node (LN) involvement in non-small cell lung cancer (NSCLC). Patients were examined in terms of demographic characteristics, preoperative and postoperative management, survival rates, as well as variables affecting survival. Surgical-pN1 localization or pleural involvement does not have a significant effect on survival, whereas advanced age and further T classification affect survival adversely. Adjuvant therapy, on the other hand, has a significantly positive effect on survival.

Mar 21, 2019

B.Sanz et al examined the link between adiponectin serum levels and frailty-related parameters. Participants were examined for their serum adiponectin levels in combination with frailty-related parameters (ie, body composition, physical fitness, cognitive function, psychological parameters, and quality of life). Lower body weight, body mass index, body fat mass, fat mass/height2, lean mass, lean mass/height,2 and smaller waist and hip circumferences were reported in relation to higher serum adiponectin levels in women. In men, an inverse association of better cognitive function with adiponectin was observed. In women, a higher concentration of adiponectin was associated with decreased anxiety. In this study population, there was evidence of an association of adiponectin with body composition, cognitive function, and anxiety, with differential links by sex.

Mar 21, 2019

This is a retrospective case series of all tonsillectomies performed in patients <15 years old in the Auckland region during 2017 was performed. Demographic, clinical, and surgical data were extracted and analyzed. A total of 2177 tonsillectomies were performed during the study period. The overall PTH rate was 3.6% occurring within the first 24 hours (primary) and 3.4% after 24 hours (secondary)). Meantime to PTH was 6.6 ± 3 days (range: 1-16 days). These results show that PTH rates in Auckland remain within acceptable limits according to the literature.

Mar 21, 2019

The aim of this study was to investigate the clinical and radiological outcomes of the patients who have received short and long fusion for adult spinal deformity (ASD). A total of 21 patients who received surgical reconstructive spinal fusion procedures. This study elucidated that to acquire harmonious spinal alignment and favorable clinical outcomes, long fusion is better than short fusion. extreme lateral interbody fusion (XLIF)  demonstrated a strong ability to reconstruct the deformity on intervertebral space that is better to apply as much as possible. For ASD patients with complications, short fusion can be one of the options.

 

Mar 21, 2019

This retrospective study was conducted to assess the relationship of specific ultrasound characteristics and macroscopic features of confirmed malignant pleural effusion (MPE), thus increasing the diagnostic potential of thoracic ultrasound. The incidence of specific combinations of the ultrasound characteristics and macroscopic appearance of MPEs showed different frequency distributions, which may improve the diagnostic value of thoracic ultrasound in this patient population.