Research Desk

Jun 25, 2019

Jake Claflin, et al. sought to determine the intraoperative parathyroid hormone criteria correlated with the lowest rates of persistent hyperparathyroidism after parathyroidectomy for primary hyperparathyroidism. Patients with a lowest intraoperative parathyroid hormone ≤40 pg/mL compared with the traditional criteria of a ≥50% decrease from baseline and a final parathyroid hormone in the normal range (<65 pg/mL) had the lowest rates of persistent primary hyperparathyroidism after parathyroidectomy.

Jun 25, 2019

Investigators tried to calculate the prevalence of visits assigned an explicit or suggestive medical diagnosis code (ICD-9-CM) for CSA and compare the demographic profile of ED visits by coding type. Their study demonstrates one method for identifying CSA cases, which has the potential to increase surveillance of victims in the ED. Results imply that explicit codes alone may overlook most cases, whereas use of suggestive codes may identify additional cases, and proportionally more young and male victims.

Jun 21, 2019

This prospective and comparative study is to evaluate the efficacy of extracorporeal shockwave therapy (ESWT) in the treatment of cellulite in the gluteus and posterior of the thigh. The results presented demonstrated the effectiveness and safety of ESWT in the treatment of cellulite and in the decrease of the degrees, improvement of the aspect of the skin, and reestablishment of quality of life.  

Jun 20, 2019

Researchers investigated nephrotoxicity related to initial vancomycin dose in patients with severe renal dysfunction. Their data suggests that vancomycin loading doses do not increase nephrotoxicity compared with lower doses in patients with severe renal dysfunction.

Jun 20, 2019

A systematic review assessed the impact of orthognathic surgery on patient satisfaction, overall quality of life, quality of life related to oral health, and to orthognathic surgery in particular, among adult patients. It concluded that Orthognathic surgery results in improvements in quality of life both physically and psychosocially after surgery and is associated with high rates of patient satisfaction.

Jun 20, 2019

Researchers compared Retrograde Intrarenal Surgery(RIRS) and Percutaneous nephrolithotomy(PNL) in the management of 4 cm sized kidney stones. They found that PNL is an effective method and operation time is lower than RIRS. Also a second oper­ation for JJ stent taking is lower in PNL. RIRS is a safe method. RIRS has less complications and hospitalization time.

Jun 20, 2019

Jordyn T. Wallenborn, et al. investigated the relationship between marital disruptions and internalizing disorders of children in a prospective cohort. They found that parental marital status is associated with an increased CBCL internalizing behavior score at 3 years of age, but the association disappears at later time points.

Jun 20, 2019

Retrospective comparison of non-structural and structural bone graft in single segment thoracic tuberculosis surgery revealed that non-structural bone graft can reduce operation time, blood loss, but has longer hospital stay and the correction and loss of Cobb angle of non-structural bone graft are both smaller than structural bone graft.

Jun 19, 2019

Joseph P Samuel et al sought to study the longitudinal outcome and predictors of seizure outcome following FLE surgery of the patients. Duration of epilepsy of fewer than 2 years before surgery was observed as a significant predictor for the achievement of freedom from the seizure emphasizing early surgery for a better outcome in frontal lobe epilepsy. For long-term outcome, post-operative EEG remained a good predictor

Jun 19, 2019

Natasha Josifovska et al sought for a reliable clinical marker which can be a putative marker for retinal detachment (RD) as well as prognostic factor for surgical success or outcome, following identification of molecular markers such as presence of inflammatory cytokines in the subretinal fluid (SRF), and the effect of SRF upon dead cell clearance in the retina. Optical coherence tomography (OCT) was performed on 12 patients with rhegmatogenous RD (rRD) before and after 23G vitrectomy for RD. They collected pure SRF during surgery and analyzed it by protein array profiling on a panel of 105 inflammatory cytokines (Human XL Cytokine Array). Quantification of the effect of SRF upon human macrophages-driven phagocytosis of apoptotic retinal pigment epithelial (RPE) cells ex vivo was done by flow cytometry. As per findings, presence of hyperreflective points (HRPs) at the detached neuroretina border on OCT are the hallmark of fresh RD; successful reattachment surgery leads to a reduction of the size and number of the HRPs, and these likely resemble the macrophage conglomerates seen by immunohistochemistry. Thy noted progenitor/stem-like cells and signs of inflammatory reaction in the neuroretina in RD, while the SRF displayed inflammatory cytokines and other factors which enhance the ability of professional phagocytes to engulf dying RPE, or for that matter, other dying cells in the retina.