Clinical research aims to examine the effectiveness of theory-based behavioral (provider-level) and implementation (practice-level) bundled interventions versus enhanced usual care (AAP based oral health education) delivered by providers at well-child visits (WCVs) in increasing dental attendance among 3-6 year old Medicaid-enrolled children.
The efficacy of two highly requested treatments for children with autism spectrum disorder, both of which are directed at increasing functional skills and reducing maladaptive sensory behaviors are being studied in a trial. They are occupational therapy using sensory strategies for decreasing sensory dysfunction and applied behavioral analytic (ABA) therapy.
The safety, efficacy, and tolerability of H2NVAC in patients with HER2-expressing ductal carcinoma in situ (DCIS) is being evaluated in order to prevent future invasive breast cancer among patients who are diagnosed with DCIS.
New York University School of Medicine has undertaken a retrospective cohort study that seeks to measure the effect of PRIM-ER on older adults with serious illness on aspects of ED disposition to an acute setting, healthcare utilization in the 6 months following the index ED visit, survival following the index ED visit,and determine site, provider, and patient-level characteristics that are associated with variation in impact of PRIM-ER across sites.
Shenzhen Geno-Immune Medical Institute is conducting a Phase I/II clinical trial of gene therapy for treating X-linked adrenoleukodystrophy using a high-safety, high-efficiency, self-inactivating lentiviral vector TYF-ABCD1 to functionally correct the defective gene. The objectives are to evaluate the safety and efficacy of the gene transfer clinical protocol.
Assistance Publique Hopitaux De Marseille is conducing a study to evaluate the effectiveness of Smoke Electroprecipitation device in laparoscopic cholecystectomy for cholecystitis. It is an intervention for a common pathology where smoke is particularly important due to the tissue inflammation and due to the extensive dissection necessary to perform the surgical procedure.
Beth Israel Deaconess Medical Center is conducting an Observational study in 245 participants to monitor fracture risk associated with bone tumors in cancer patients.
Hôpital le Vinatier is conducting an Interventional Study in 10 participants to focus on specific emotion recognition components, pen and paper or role playing tasks focusing on the same processes, a proposal of a home-based task in mental operations that enable people to perceive, interpret constantly changing social informations.
University of Wisconsin, Madison is conducting a randomized, double-blind, placebo-controlled, parallel group trial which will study the effects of omalizumab on patients with 2 or more episodes of Idiopathic Angioedema (IAE) in the past 6 months, despite current therapy.