The purpose of this repository is to collect tissue and blood specimens of non-melanoma skin cancers for future studies. The aim is to create a single, annotated bio-repository of non-melanoma skin cancers. Additionally, they may create cell lines and patient-derived tumors from collected samples. This study is going to lead by Dr. Aaron Mangold.
The purpose of this observational study is to find out what immune system processes cause the chronic inflammation that happens with chronic rhinosinusitis (CRS) and if there are different immune system pathways involved among CRS patients. This study is going to lead by Dr. Rohit Divekar.
This phase III, double-blind, randomized, placebo-controlled trial compares the effects, good and/or bad, of sorafenib tosylate in treating patients with desmoid tumors or aggressive fibromatosis. Sorafenib tosylate may stop the growth of tumor cells by blocking some of the proteins needed for cell growth.
A phase 3 randomized, double-blind, multi-dose, placebo-controlled study to evaluate the long-term safety and the efficacy of Fasinumab in patients with pain due to osteoarthritis of the knee or the hip. Participation in this research study of an investigational drug could last up to 18 months and include approximately 17 clinic visits.
This research study will test different doses of RG-HRV16 to find the minimum dose needed to give research subjects cold symptoms of at least moderate intensity. The study will also test the safety of RG-HRV16. This study represents a first-in-human, phase 1 study to assess the safety of RG-HRV16 in humans and identify the dose needed to produce moderate-to-severe colds in 75% of HRV16-seronegative human volunteers.
This Study will test the use of a short virtual reality is driven goggle test as a means of detecting mTBI in a diverse group of athletes.
The purpose of this trial is to evaluate the performance of a new diagnostic device in the diagnosis and management of glaucoma. We will use this new device (PERG) to evaluate the function of the retina in glaucoma patients. This device is safe for patients.
The purpose of this study is to evaluate the clinical feasibility and safety of the ICESENSE3TM cryotherapy system for the ablation of small malignant invasive breast tumors.
Gastric bypass surgery has been proposed as an effective treatment strategy for type 2 diabetes mellitus (T2DM), but thus far algorithms for the management of T2DM immediately after surgery have not been established. The investigators designed an algorithm to achieve good glycaemic control in patients with insulin-requiring T2DM upon discharge after gastric bypass surgery and evaluated this algorithm for feasibility, efficacy, and safety
The International study on NoSocomial Pneumonia in Intensive CaRE (PneumoINSPIRE) is a prospective, international, multicentre, observational, cohort study. The study aims to provide up-to-date and generalisable information on current worldwide epidemiology and clinical practice associated with diagnosis and management of nosocomial pneumonia in Intensive Care Unit (ICU) patients. PneumoINSPIRE study is endorsed by the European Society of Intensive Care Medicine (ESICM).