National Human Genome Research Institute is conducting a study in 1500 participants to examine rare congenital disorders that involve malformations and abnormal growth. The study focuses on patients with Proteus syndrome, whose physical features are characterized by overgrowth, benign tumors of fatty tissue or blood vessels, asymmetric arms or legs, and large feet with very thick soles.
Bayer is conducting an Observational study in 1000 participants to gain more information on treatment patterns of patients treated with Xarelto in combination with acetylsalicylic acid. The study will also look into treatment outcomes for patients being treated with a combination of Xarelto and ASA by their physicians.
University Hospital Inselspital, Berne is conducting an interventional trial in about 15 participants in order to analyse the efficacy of GlucoTab® for glycaemic management in Type 2 Diabetes patients using insulin degludec. The study includes patients with HbA1c between 6.5 - 10.0%.
Centre Hospitalier Universitaire de Besancon is conducting an obeservational study in 60 participants in order to describe the proportion of patients with ulcerative colitis treated with vedolizumab who achieve mucosal healing at week 54 of treatment.
M.D. Anderson Cancer Center is conducting a Single Group Assignment study in 100 participants in order to to learn if using 2 different kinds of contrast agents (Eovist [gadoxetate] and Gadovist [gadobutrol]) given at the same time is better than using 1 contrast agent alone in learning which liver lesions may be cancerous.
The purpose of this study is to investigate the ability of alvimopan to reduce the time to return of bowel function in patients undergoing cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. Half of the participants will receive alvimopan or and half will receive placebo immediately before and for up to seven days after surgery.
This study by the Northwestern University at Chicago is investigating whether changes in the shape and size of bodily muscles and spinal cord anatomy can influence recovery rates following a motor vehicle collision (MVC). The objective is to demonstrate that the presence of muscle and spinal cord degeneration and associated muscle weakness is the consequence of a mild MVC-related injury involving the cervical spinal cord.
University of Kentucky College of Dentistry, United States is conducting a 14 week long clinical radiographic and Histomorphometric study on 40 participants. The primary aim of the study is to assess the quality of the newly formed bone at 14 weeks the time of implant placement by comparing the percentage of new vital bone in the histomorphometric analysis.
Mayo Clinic has undertaken a clinical trial in which a team of investigators headed by Michelle Clarke, M.D., is anticipating a reduction in the incidence and duration of postoperative urinary retention by adding tamsulosin and thereby produce a reduction in morbidity related to the treatment of urinary retention as well as shortened hospital stays.
The effect of transcranial direct current stimulation (tDCS) on the clinical status of Internet game addiction is being evaluated by researchers at SMG-SNU Boramae Medical Center, Republic of Seoul, Korea. They have hypothesized that real stimulation with tDCS on the dorsolateral prefrontal cortex will have higher effectiveness on the severity of addiction symptom, subjective craving for gaming, response inhibition and cue reactivity rather than sham stimulation with tDCS.