National Human Genome Research Institute (NHGRI) is conducting an Observational Perspective study in 2000 participants in order to identify the genetic cause of disorders that are difficult to identify with existing techniques and to develop best practices for the medical and counseling challenges of whole genome sequencing.
Bayside Health is conducting a Randomized trial in 172 participants to the urgent need to identify a medical treatment able to limit progression of abdominal aortic aneurysms. Primary outcome includes abdominal aortic aneurysm maximum orthogonal diameter in a time frame of 12 months.
Uppsala University is conducting an Observational study in 40 participants to understand the biological changes in pancreatic tumors over time, which will be measured by patient symptoms, biochemistry, contrast enhanced computed tomography, DOTATOC-PET, FDG-PET and core needle biopsy with histopathological analysis.
Karolinska Institutet is conducting an Interventional study in 1000 participants to assess the effectiveness of Diclofenac for prevention of post-ERCP pancreatitis. Primary outcome measure includes assessment of Post ERCP Pancreatitis, in a time frame of 30-days post ERCP.
Dana-Farber Cancer Instituteis conducting an Interventional Single Group Assignment Trial in 30 participants in order to evaluate the role of cryoablation (the removal of diseased tissue using extreme freezing temperatures) as a possible treatment for head, neck and spine tumors.
NIDCR funded clinical trial headed by Niki M Moutsopoulos, D.D.S., focuses on the oral bacteria and genetic immune problems of different people to learn how these affect gum disease and other conditions of the mouth.
The Department of Oncology at Rigshospitalet Copenhagen, Denmark, has undertaken a study which aims to identify genetic variations in survivors of testicular cancer and connect these variations to differences in risks of late effects.
The University of Minnesota is carrying out a study to identify the patterns of brain activity in reward circuitry that promote symptoms of anorexia nervosa. This project will compare weight-restored individuals with anorexia nervosa to a non-eating disorder control group on reward brain circuitry patterns in response to typically rewarding cues and disorder-specific restrictive eating cues using fMRI.
The feasibility of performing High-Resolution Intravital Microscopy (HIVM) in patients with deep space solid tumors during the standard course of surgical resection is being evaluated in a study which is being conducted by the Mayo Clinic.
Indiana University School of Medicine is carrying out the ACCESS Trial is a national, multi-center research study funded by the National Institutes of Health’s National Heart, Lung and Blood Institute. The study aims to determine the best method of care for survival and neurological recovery for patients resuscitated after cardiac arrest due to ventricular fibrillation (VF) outside of the hospital, but who have no evidence of a heart attack on a heart scan, called an electrocardiogram (ECG).