Mayo Clinic is carrying out a study with the aim to define a set of differentially regulated secreted proteins in human cancer cells across all stages of cancer progression. If the pilot is successful, they plan to expand the data set to 100 subjects and include Squamous Cell Carcinoma (SCC)s of various differentiation and anatomical location and also nclude SCCs from transplant patients.
Queen Charlotte and Hammersmith Hospital, London, United Kingdom is conducting a pilot study to assess accuracy of histological diagnosis using ultrasound-guided biopsy for women with suspected endometrial cancer as an alternative to hysteroscopy guided biopsy.
Investigators at Mayo Clinic are set to compare magnetic resonance (MR) elastography measurements to other forms of noninvasive methods of detecting raised intracranial pressure, including optical coherence tomography (OCT) imaging measurements of the retinal nerve fiber layer (RNFL) and indirect signs of raised intracranial pressure on magnetic resonance imaging (MRI), in a Clinical Trial.
The precise cause of otosclerosis is not known though genetic factors and viral infections may play a role. In the last year, research from Belgium and Holland has pinpointed some genes that may increase the risk of developing the disease. The aim of this project is to see if the same genes found in the Belgian and Dutch patients also increase risk in UK patients, with the future goal of enhancing the treatment.
Stanford School of Medicine is conducting a clinical trial to test the efficacy and safety of SD-101 in subjects with Epidermolysis Bullosa. The purpose of this study is to assess whether SD-101 cream (3% or 6%) is effective in treating the lesions in subjects with Simplex, Recessive Dystrophic, or Junctional Epidermolysis Bullosa.
A study is being conducted by the National Institute of Dental and Craniofacial Research (NIDCR) To identify chronic Graft-versus-host disease (cGVHD) in the mouth and better understand the development, treatment, and progress of post-allogeneic hematopoietic stem cell transplant (HSCT) changes in the mouth.
South Egypt Cancer Institute is conducting a study to analyze information retrospectively on malignancies primarily occurring in the pelvis/ pelvic organs of paediatric patients. It aims to categorize and record the spectrum of these malignancies as separate disease entities, calculate their relative incidence and verify the treatment outcomes.
The Children's Hospital Medical Center at Cincinnati is carrying out an interventional prospective study to observe the effects of an elemental diet in adult patients suffering from Eosinophilic Gastroenteritis. The study includes men and women between the age group of 18 - 65 years.
Two primary care friendly methods will be compared in an interventional study being conducted by Stanford University to deliver an effective non- pharmacological intervention i.e. cognitive behavioral therapy to middle aged and older insomnia patients.
The REDUCE-IT Trial revealed that administration of icosapent ethyl 2 g twice daily surpassed placebo in reducing high Triglyceride(TG) levels, Cardiovascular(CV) events, and CV death in patients with high TGs and previously diagnosed CV disease or those at high risk for developing it, and those who were already on statin therapy with relatively stable LDL levels.