Research Desk

Oct 18, 2019

This is a a case of thoracic spinal Atypical teratoid rhabdoid tumors in a three-year-old boy who presented with a ten-day history of back pain and progressive weakness of the lower extremities and an inability to walk. The tumor showed characteristic aggressive progression until managed with intensive multimodal therapy to achieve durable long-term remission. 

Oct 18, 2019

 A 43-year-old man in 2014 was diagnosed with oral squamous cell carcinoma involving the tongue. He underwent extensive surgery that involved right tongue cancer resection and reconstruction with a free flap graft from his right forearm. He then was started on chemotherapy and radiation. A biopsy of the mass revealed metastatic squamous cell carcinoma. He was deemed to not be a surgical candidate and continued on palliative chemotherapy. 

Oct 18, 2019

A 50-year-old male with a history of hyperthyroidism, hypertension, and congestive heart failure presented to another hospital with fever and altered mentation. He was found to have pneumonia on imaging and was started on antibiotics. He developed shock complicated by atrial fibrillation with rapid ventricular rate which was treated with amiodarone. The endocrinology team determined he was in thyroid storm. His medical treatment of thyroid storm was aggressively titrated to maximal therapy. But this was followed by transaminitis, respiratory failure requiring intubation, shock requiring vasopressor support, kidney failure requiring continuous renal replacement therapy, and heart failure.

Oct 18, 2019

An 85-year-old male patient presented for investigation of iron deficiency anaemia. Initial upper endoscopy found a subepithelial duodenal lesion with central depression but otherwise normal appearing mucosa. Superficial biopsies of the duodenal lesion were unremarkable. Subsequent antegrade single balloon enteroscopy revealed active bleeding from the lesion which was refractory to endoscopic treatment.

Oct 18, 2019

This is a case of a 79-year-old man, with a history of HCV-related cirrhosis who came for an abdominal ultrasound which showed  biliary tract dilatation. Later on detailed investigations revealed that it was a of  variant “corkscrew aorta” involved the abdominal subrenal tract. 

Oct 16, 2019

This is a case of a 27-year-old male patient with recurrent respiratory papillomatosis who was treated with CO2 laser therapy followed by 5-aminolevulinic acid photodynamic therapy (ALA-PDT). There was no adverse reaction after treatment and no recurrence during the follow-up time.

Oct 16, 2019

This is a case report of a 59-year-old man was admitted because of sudden blurring of vision, progressive proptosis of the left eye, and mild double vision in left and down directions of the gaze (Hess-Lancaster test). On examination, the best-corrected visual acuity decreased from 8/20 to 1/50 in one week. There was a swelling of the left upper eyelid. A hard and tender mass was palpated in the superior temporal left orbit. USG showed an extraconal solid mass, situated in the superior lateral corner of the orbit. CT & MRI revealed a mass of two centimeters in diameter, with a round well-defined outline, within the lacrimal gland. We performed an enucleoresection of the mass, via a coronal approach and a lateral orbitotomy by a piezosurgical device. The lesion appeared nodular, brownish, measuring about 2 × 1.5 cm. Histopathological findings were consistent with acinic cell carcinoma with a microcystic, focally papillary-cystic growth of pattern. Follow-up MRI outcomes led to the removal of the residual lacrimal gland for suspicion of recurrence. 

Oct 14, 2019

A 49-year-old male presented to the emergency department at Bascom Palmer Eye Institute complaining of right eye pain and decreased vision about 17 h after being struck in the eye with a tree branch. On examination, he was noted to have a 1.5-mm corneal laceration with fibrin in the anterior chamber and signs of traumatic cataract with posterior synechiae and pigment on the anterior lens capsule. No signs of endophthalmitis were noted on B-scan. The laceration was repaired, and the patient was treated prophylactically with intravitreal ceftazidime 2.25 mg, vancomycin 1 mg, and voriconazole 50 μg. Aqueous humor cultures for fungi and bacteria were negative, and B-scan was unremarkable at initial follow-up.

Oct 14, 2019

Charmaine C. W. Lo et al presents the case of a 33-year-old female who was managed at our center for adenoid cystic carcinoma of the Bartholin's gland. She presented with a prolonged history of a vulvar lesion which was eventually diagnosed as adenoid cystic carcinoma of the Bartholin's gland. She was subsequently treated with wide local excision of the primary and inguinal lymph node dissection followed by adjuvant radiotherapy and chemotherapy. She had a gross perineural invasion on MRI imaging. The present case highlights the diagnostic dilemma in this extremely rare cancer and the literature further explores the natural history and treatment options.

Oct 14, 2019

A 10-year-old black South African boy presented with a long-standing history of fatigue; he had a heart murmur, and a bounding pulse and wide pulse pressure. An echocardiogram demonstrated a large coronary cameral fistula involving his left coronary artery and his left ventricle. This was also confirmed on ascending aortogram. Surgical ligation was done and his symptoms improved afterward, but a small residual fistula remained.