Research Desk

Sep 07, 2019

Objective: The aim of the Journal of Pediatric Endocrinology and Metabolism (JPEM) is to diffuse speedily new medical information by publishing clinical investigations in pediatric endocrinology and basic research from all over the world. JPEM is the only international journal dedicated exclusively to endocrinology in the neonatal, pediatric and adolescent age groups. JPEM is a high-quality journal dedicated to pediatric endocrinology in its broadest sense, which is needed at this time of rapid expansion of the field of endocrinology. JPEM publishes Reviews, Original Research, Case Reports, Short Communications and Letters to the Editor (including comments on published papers),. JPEM publishes supplements of proceedings and abstracts of pediatric endocrinology and diabetes society meetings.

Topics

  • Pediatric endocrinology
  • Pediatric diabetes
  • Inherited metabolic diseases

Article formats

Original Research, Reviews, Mini Reviews, Opinion Papers, Case Report, Short Communications, Letters to the Editor (including comments on published papers), Book Reviews.

Jul 22, 2019

In this study, they investigate whether early changes in energy-related metabolites in the blood - measured shortly after chemotherapy - could be used to identify patients who developed heart toxicity at a later time. They found that metabolites associated with the energy powerhouse of the cell - the mitochondria - changed differently in patients who later developed heart dysfunction compared to those who did not.

 

Jul 22, 2019

Infants who develop eczema are more likely to develop food allergies, hay fever, and asthma as they grow older, a progression known as the atopic march. They identified itching and dry cracked skin of eczema patients as a significant promoter of the atopic march. Moisturizers, especially early in a child's life, may help prevent eczema, food allergies and other allergic diseases.

Jul 22, 2019

Osteosarcoma (OS) is genetically similar in dogs and human children, according to the results. TGen and Tufts researchers sequenced the genomes of 59 dogs, finding that canine OS shares many of the genomic features of the human OS, including low mutation rates, structural complexity, altered cellular pathways, and unique genetic features of metastatic tumors that spread to other parts of the body.

Jul 22, 2019

Institut Jerome Lejeune is conducting a study in 47 participants in order to assess the hypothesis that  alveolar hypoventilation may be due to ventilatory control disorders caused by dysautonomia, but also to a decrease in the strength of the respiratory muscles within the framework of the global muscular hypotonia described in children with Down syndrome. Patients between ages 4-16 will be included. 

Jul 22, 2019

Assistance Publique Hopitaux De Marseille is conducting a study in 316 participants to investigate the hypotheseis that extracellular volume fraction measurement could be used as an early predictor of LV dysfunction in the left-sided valve regurgitations.

Jul 22, 2019

A new study has concluded that people who wear a hearing aid for age-related hearing problems maintain better brain function over time than those who do not. The findings provide early evidence that encouraging people to wear an effective hearing aid may help to protect their brains and reduce their risk of dementia.

Jul 22, 2019

Institut Paoli-Calmettes is conducting an Observational study in 3000 participants in order to built a database of Institut Paoli-Calmettes patients diagnosed with thyroid cancer. These patient characteristics will be collected in order to set up prospective and retrospective studies. All the patients who come to the centre over a time frame of 10 years will be considered. 

Jul 22, 2019

Patients with cystic fibrosis (CF) who take ivacaftor appear to have fewer respiratory infections over time than those not taking the drug, according to new research. In this study by using data from a CF registry in the U.K., the authors compared CF patients (age six and older) who took ivacaftor with those CF patients who did not take the drug over a three-year period.

Jul 22, 2019

Henan Cancer Hospital is conducting a study in 100 participants in order to evaluate the safety and efficacy of domestic injection paclitaxel (albumin binding type) in patients with advanced digestive tract tumors,and to further explore the possible predictors of efficacy.In order to provide more effective chemotherapeutic drugs, prolong survival time and improve quality of life for patients with advanced digestive tract tumors.