Clinical Orthopaedics and Related Research® is a leading peer-reviewed orthopaedic journal and a publication of The Association of Bone and Joint Surgeons®. CORR® brings readers the latest clinical and basic research and informed opinions that shape today's orthopaedic practice, thereby providing an opportunity to practice evidence-based medicine.
Researchers reports that the heavy reliance of these other site tumors on a specific metabolic pathway presents a potentially new therapeutic against these lethal tumors. Analysis of brain metastases and comparison of those tumors to others that had spread to different parts of the body was the first such application of advanced RNA sequencing and uncovered a variety of factors that make tumors in the brain so difficult to treat.
This book is an unique but practical case-driven guide to a variety of pediatric dermatology diseases observed over long periods. It features a broad range of cases covering initial presentation during infancy and the subsequent developments of through childhood, adolescence and adulthood. Disease cases include papulosquamous disorder, hereditary cornification, exanthematous diseases and viral infections of the skin.
This book provides a comprehensive, practical, and timely guide to neurorehabilitation for patients affected by tumors of the central nervous system. The book is structured in two main parts - the first is devoted to the basics of cancer and to the main clinical features of the tumors of the nervous system, as well as to the essentials of therapeutic approaches & the second part is dedicated to rehabilitation issues, providing the tools for health personnel to take in charge persons affected by neuro-oncological disease.
This text reviews the current understanding of vestibular anatomy allowing for a framework of reference, and how it's applied to vestibular testing, diagnosis and management of dizziness. This text serves as a complete reference for clinicians, students and researchers interested in this common and severe disorder allowing for improved patient care and advancement of knowledge in the field.
A study aimed to determine the predictors of burnout syndrome amongst medical students in Cameroon. 413 medical students were recruited consecutively after sampling three of the five medical schools. It was found that It was found that marital status significantly predicted burnout, as well as relationship difficulties, cumulative GPA, regretting the choice of medical studies, etc. and early detection of burnout in medical students could be done by identifying and addressing the potential determinants.
A study was conducted to identify biological or clinical variables able to predict or rule out significant pathology on abdominal CT in patients presenting to an emergency department with acute abdominal pain. It revealed that the high specificity of the association between leukocytosis and relative lymphopenia amongst the study population suggests that these parameters would be sufficient to justify an emergency CT.
A study examined risk factors and outcomes of hospital readmission following complex hepatopancreatobiliary (HPB) surgery among the elderly. It was found that roughly 1 in 7 elderly patients were readmitted within 30 days and 1 in 4 patients within 90 days. Elderly patients with multiple comorbidities were more likely to be readmitted at non-index hospitals.
Researchers assessed 120 candidates to estimate the independent relationship between gastric and oral Helicobacter pylori (H. pylori) colonization and dental diseases. They noted 34.2% of individuals with gastric H. pylori and 5% with oral H. pylori. They concluded that the presence of gastric and oral H. pylori in cases with good oral hygiene and moderate socioeconomic status was not significantly related to periodontal diseases.
Excessive use of nonsteroidal anti-inflammatory drugs (NSAIDs) appears to increase the risks of acute kidney injury and chronic kidney disease among active younger and middle-aged adults, according to new study findings. 764,228 active-duty US soldiers (85.8% male; median age 27 years), 17.9% received 1 to 7 defined daily doses (DDD) of NSAIDs per month and 16.3% received more than 7. Over a median 2.4 person-years, 2356 cases of acute kidney injury (AKI) and 1634 new cases of chronic kidney disease (CKD) occurred.