Research Desk

Apr 18, 2019

In this case review, vRad Chief Medical Officer, Dr. Benjamin W. Strong, utilizes cinematic and still imagery to explore the findings and diagnosis of some of his favorite cases complied from vRad’s extensive teaching library.

Apr 18, 2019

Dr, Socinski discusses new applications for immunotherapy in the treatment of patients with non–small cell lung cancer. There are 2 basic elements that providers have to get right - one is the diagnosis, which includes histology and PD-L1 status, or molecular status in stage IV disease. The second important factor is the disease stage. Socinski said that researchers are enthusiastic about the progress with these therapies in stage IV disease and are hopeful these advances can extend into earlier settings.

Apr 18, 2019

According to a new study by Washington University School of Medicine in St. Louis, the new rules for reimbursement are capable of providing a little relief to safety-net hospitals by shifting the burden towards wealthier patient populations. The new rules divide hospitals into five groups based on the proportion of their Medicare patients who are also enrolled in Medicaid. 

Apr 18, 2019

This study will serve as a pilot study to determine the efficacy and safety of two novel oral agents (clonidine, naltrexone) in the treatment of chronic, non-experimentally induced itch in atopic dermatitis. In this study, eight subjects with symptomatic atopic dermatitis will be recruited and treated with either oral clonidine (four subjects) or oral naltrexone (four subjects). Disease burden will be evaluated before and after 4 weeks of treatment through reporting of subjective symptomatology via surveys/questionnaire, neurometer study, and clinical assessment.

Apr 18, 2019

In patients with mild to moderate glaucoma and cataract, the second-generation iStent inject system, with two redesigned stents, reduces intraocular pressure (IOP) more than cataract surgery alone, according to results of a new pivotal trial. The most important finding is that the iStent inject, when done with cataract surgery, can improve the likelihood that unmedicated IOP is reduced by 20% or more compared to cataract surgery alone.

Apr 18, 2019

The purpose of this study is to evaluate safety, tolerability, pharmacokinetics, and pharmacodynamics of PF-06817024 in healthy volunteers, in participants with chronic rhinosinusitis, with nasal polyps and in participants with moderate-to-severe Atopic Dermatitis. This is a phase 1, randomized, double-blind, third-party open, placebo-controlled, dose escalating study.

Apr 18, 2019

Healthy and uncomplicated lupus pregnancies have similar immune signatures that differ from those in complicated lupus pregnancies, researchers report. Women with systemic lupus erythematosus (SLE) face an increased risk of pregnancy complications, including preeclampsia, fetal or neonatal death and fetal morbidity. Identifying women likely to experience such complications remains challenging.

Apr 18, 2019

Scientists have uncovered a molecular signaling pathway involving Stat3 and Fam3a proteins that regulates how muscle stem cells decide whether to self-renew or differentiate - an insight that could lead to muscle-boosting therapeutics for muscular dystrophies or age-related muscle decline

Apr 18, 2019

The neuropeptide oxytocin blocks enhanced drinking in alcohol-dependent rats, according to a study led by researchers at the National Institutes of Health, and The Scripps Research Institute. Targeting the oxytocin system, the authors note, may provide novel pharmaceutical interventions for the treatment of alcohol-use disorder.

Apr 18, 2019

Sasikumar Kilaikode from LSU Health Shreveport presented a talk on Obstructive Sleep Apnea in children, with respect to identifying its signs and early intervention in order to prevent complications.