New Rare Mechanism for ALL to Relapse After CAR T Cell Therapy

03 Oct, 2018 ,
University of Pennsylvania School of Medicine
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University of Pennsylvania School of Medicine
03 Oct, 2018 ,

A single leukemia cell unknowingly engineered with the leukemiatargeting chimeric antigen receptor CAR lentivirus and infused back into a patient was able to reproduce and cause a deadly recurrence of Bcell ALL Researchers found that the CAR lentivirus that would usually enter a T cell to teach it to hunt cancer also ended up binding with a leukemic cell

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