Novel Designer Probiotic Treatment For Cancer Immunotherapy

14 Feb, 2020 ,

Biochemical engineers from Columbia have designed a new probiotics strain that can seek out solid tumors and safely deliver immune checkpoint inhibitors after a single dose, resulting in tumor regression or both untreated and treated cancer lesions. The newly engineered probiotics safely deliver immunotherapies within tumors and include nanobodies against two proven therapeutic targets – PDL1 and CTLA4.